RecruitingNCT07439991

Study of Risk Factors and Prediction of Blood Clots After Lung Cancer Surgery

Prospective Cohort Study on Risk Factors and Machine Learning-Based Prediction of Postoperative Venous Thromboembolism in Patients Undergoing Lung Cancer Surgery

Sponsor

The First Hospital of Jilin University

Enrollment

900 participants

Start Date

Nov 1, 2024

Study Type

OBSERVATIONAL

Conditions

Lung Cancer (Diagnosis)Venous Thromboembolism (VTE)Deep Vein Thrombosis (DVT)

Summary

The goal of this observational study is to learn about the risk factors and prediction of postoperative venous thromboembolism (VTE) in patients undergoing lung cancer surgery. The main question it aims to answer is: Which clinical, surgical, and laboratory factors are associated with the development of postoperative deep vein thrombosis (DVT) in lung cancer surgery patients, and can machine learning models accurately predict individual risk? Participants undergoing lung cancer surgery will be prospectively followed for 30 days after surgery. Perioperative clinical data, laboratory results, and imaging findings will be collected to identify VTE risk factors and to develop a predictive model.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is identifying risk factors that predict blood clots (deep vein thrombosis or pulmonary embolism) after surgery for lung cancer. By analyzing clinical data, lab results, and imaging, researchers aim to build a better prediction tool to catch high-risk patients before clots occur. **You may be eligible if...** - You are 18 or older - You are having surgery to remove lung cancer - You are expected to stay in hospital for at least 48 hours after surgery - Your medical records from before and after surgery are available - You are willing to be followed up for 30 days after surgery **You may NOT be eligible if...** - You already had a blood clot (deep vein thrombosis or pulmonary embolism) before surgery - You have been on blood thinners for 2 weeks or longer before surgery - You have a severe clotting or bleeding disorder - You have severe liver, kidney, or blood problems, or an uncontrolled infection - You are also having another major organ surgery at the same time (e.g., heart or liver surgery) - You are pregnant or breastfeeding - Your follow-up data after surgery is incomplete Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERProspective Perioperative Data Collection

The intervention involves the prospective collection of perioperative clinical, laboratory, and imaging data from adult patients undergoing lung cancer surgery. No therapeutic or diagnostic procedures beyond standard care are applied. Collected data will be used to identify risk factors for postoperative deep vein thrombosis (DVT) and to develop machine learning-based predictive models.

Locations(1)

The First Hospital of Jilin University, Department of Thoracic Surgery

Changchun, Jilin, China

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NCT07439991

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