Role of Pro-Resolving Lipid Mediators in Obesity-Associated Diseases

This study is investigating a class of natural anti-inflammatory molecules called pro-resolving lipid mediators, and whether their levels are different in postmenopausal women with obesity and in those with breast cancer. The goal is to understand how these molecules relate to inflammation in obesity-related diseases. **You may be eligible if (Healthy participants):** - You are postmenopausal (at least 1 year without a period) - You are of normal weight, overweight, or obese - You have no personal history of cancer - Your weight has been stable for the past 3 months **You may be eligible if (Breast cancer participants):** - You are postmenopausal - You have early-stage luminal breast cancer (Stage I or II) requiring surgery without pre-operative treatment **You may NOT be eligible if:** - You have a personal history of cancer (healthy group) - You are currently on a weight loss program, have had bariatric surgery, or are taking diabetes or hormone replacement medications - You have significant gastrointestinal disease, liver disease (other than fatty liver), heavy alcohol use, or psychiatric impairment - Your breast cancer is Stage III or higher Talk to your doctor to see if this trial is right for you.