RecruitingNot ApplicableNCT07451600

Effectiveness of TMS on Spasticity and Balance for Patients With MS

The Effect of Transcranial Magnetic Stimulation on Spasticity and Balance in Patients Diagnosed With Multiple Sclerosis


Sponsor

Ankara Etlik City Hospital

Enrollment

24 participants

Start Date

Mar 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Recently, non-invasive brain stimulation modalities such as transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation have become treatment options. Among these methods, rTMS is a non-invasive brain stimulation technique that can affect descending corticospinal pathways, thereby modulating cortical excitability in the motor area where it is applied. This study will examine the effect of rTMS application on spasticity and balance in patients with multiple sclerosis. In addition, the indirect effects of the applications on gait pattern, joint range of motion, and pain will be evaluated.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether a brain stimulation technique called transcranial magnetic stimulation (TMS)—which uses magnetic pulses applied to the scalp—can reduce muscle stiffness (spasticity) and improve balance in people with multiple sclerosis (MS). TMS is a non-invasive, painless procedure done in a clinic. **You may be eligible if...** - You are between 18 and 60 years old - You have been diagnosed with MS for at least 6 months - You have mild to moderate muscle stiffness in a limb (rated 1–3 on a standard scale) - You are willing to voluntarily participate **You may NOT be eligible if...** - You have serious heart, lung, or other major health problems - You have a pacemaker, metal implants in your body, or a heart rhythm disorder - You are pregnant - You have epilepsy or a history of seizures - You have a history of alcohol use or another neurological diagnosis besides MS - Your medications have changed in the last 6 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICErTMS

Low frequency rTMS application on M1 cortex

DEVICEsham rTMS

Low frequency sham rTMS


Locations(1)

Ankara Etlik City Hospital

Ankara, Yenimahalle, Turkey (Türkiye)

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07451600


Related Trials