RecruitingPhase 1Phase 2NCT07451613

Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

Phase 1B/2A Study of the Safety and Tolerability of Human Neural Stem Cells for Huntington's Disease

Sponsor

Leslie Thompson

Enrollment

21 participants

Start Date

Apr 6, 2026

Study Type

INTERVENTIONAL

Conditions

Huntington Disease

Summary

The purpose of this research study is to determine whether an implantation of hNSC-01 is a safe and tolerable study intervention for Huntington's disease. This study is the first time that hNSC-01 is being tested in people.

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria5

Please note this may not be a complete list of eligibility criteria.
Have decision-making capacity and be able to provide written informed consent.
Are between 18 to 65 years of age
Have genetically confirmed diagnosis of Huntington's Disease
Able to undergo MRI scans, tolerate neurosurgical procedure, blood draws and lumbar puncture.

Exclusion Criteria3

Are pregnant
Test positive for human immunodeficiency virus (HIV), hepatitis C or chronic hepatitis B at Screening
Have an implanted deep brain stimulation device.

Interested in this trial?

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