RecruitingNot ApplicableNCT07497425

Neuroimmune Responses to Exercise in Chronic Back Pain

Neuroimmune Responses to Physical Exercise Training in Chronic Primary Low Back Pain

Sponsor

McGill University

Enrollment

216 participants

Start Date

Jun 1, 2025

Study Type

INTERVENTIONAL

Conditions

Chronic Low Back Pain (CLBP)

Summary

The goal of this mechanistic clinical trial is to learn how physical exercise affects the body and brain in people with chronic low back pain. The study will examine whether a 12-week online exercise program changes these measures compared with a waitlist group. Researchers will also study immune activity and brain function in people with chronic low back pain and compare them with healthy participants. Participants will complete questionnaires, provide blood samples, and undergo brain imaging scans.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Physical Exercise for people with chronic low back pain (clbp). The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALPhysical Exercise

Patients in the PE training group will perform a 12-week online program comprising three 60-minute weekly training sessions. The training program is delivered by certified kinesiologists through a secured online platform. Healthy controls will participate only in the first 2 weeks of PE training.