Mental Disorder Clinical Trials

169 recruitingLast updated: June 18, 2026

There are 169 actively recruiting mental disorder clinical trials across 39 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1. Top locations include Los Angeles, California, United States, Paris, France, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Mental Disorder Trials at a Glance

169 actively recruiting trials for mental disorder are listed on ClinicalTrialsFinder across 6 cities in 39 countries. The largest study group is Not Applicable with 89 trials, with the heaviest enrollment activity in Los Angeles, Paris, and Boston. Lead sponsors running mental disorder studies include Chinese University of Hong Kong, Centre Hospitalier St Anne, and Hôpital le Vinatier.

Browse mental disorder trials by phase

Treatments under study

About Mental Disorder Clinical Trials

Looking for clinical trials for Mental Disorder? There are currently 30 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mental Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mental Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 169 trials

Recruiting
Phase 2

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Phase 3

Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder

GRIN-related Neurodevelopmental Disorder
GRIN Therapeutics, Inc.100 enrolled28 locationsNCT07224581
Recruiting
Not Applicable

Implementation of REFOCUS Training Program in Mental Health Services

Mental Disorders
Hôpital le Vinatier760 enrolled1 locationNCT05824234
Recruiting
Not Applicable

Homelessness and Prevalence of Neurodevelopmental Disorders

Neurodevelopmental Disorders
Hôpital le Vinatier150 enrolled1 locationNCT06869915
Recruiting

Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders

SleepNeurodevelopmental DisorderNeurological Disorder+1 more
National Institute of Mental Health (NIMH)1,000 enrolled1 locationNCT01778504
Recruiting
Not Applicable

Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function

PsychopathologyAnxiety DisordersMental Disorders+3 more
Northwestern University500 enrolled1 locationNCT07641244
Recruiting

Neuraxial Labor Analgesia and Offspring Neurodevelopment

Pregnant womenNeurodevelopmental DisordersLabor Pain+2 more
Dong-Xin Wang4,645 enrolled2 locationsNCT04964206
Recruiting

Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations

Healthy ChildrenChildren With Neurodevelopmental DisordersChildren With Neuropsychiatric Disorders+1 more
National Institute of Mental Health (NIMH)244 enrolled5 locationsNCT04639830
Recruiting
Not Applicable

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

Depression - Major Depressive DisorderMental DisorderCannabis Use Disorder
Massachusetts General Hospital80 enrolled1 locationNCT06878859
Recruiting

Perinatal Covid-19 Infection, NO Pathway, and Minipuberty

Neurodevelopmental DisordersNewborn, Infant, Disease
University Hospital, Lille180 enrolled2 locationsNCT04952870
Recruiting
Phase 2Phase 3

Virtual Menstrual Pain Approaches in Females

Digital HealthAcupressureMetabolomics+5 more
Nanyang Technological University145 enrolled1 locationNCT07497711
Recruiting
Not Applicable

SAFE Early Intervention for At-Risk Infants

PretermNeurodevelopmental Disorder (Diagnosis)High Risk Infant
Gazi University34 enrolled1 locationNCT07596147
Recruiting
Not Applicable

Stimulation-Induced Changes in Fronto-Limbic Network

EpilepsyMental Disorders
University of Alabama at Birmingham30 enrolled1 locationNCT05854160
Recruiting
Not Applicable

Integrated Mental Health Care for Pregnant Women With HIV in Kenya: The Tunawiri Study

Human Immunodeficiency VirusMental Disorder
University of Colorado, Denver900 enrolled1 locationNCT06117163
Recruiting
Not Applicable

PTSD Treatment for Veterans With Serious Mental Illness to Improve Functional Outcomes

Stress Disorders, Post-Traumatic; Mental Disorders
VA Office of Research and Development48 enrolled1 locationNCT05674617
Recruiting
Not Applicable

Effectiveness of the COPCA Program in Infants at Risk of Neurodevelopmental Disorders

Neurodevelopmental DisordersNeurodevelopmental Disorders and Developmental Abnormalities
University of Seville40 enrolled1 locationNCT07387627
Recruiting

Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment Outcomes of Severe Mental Disorders

SchizophreniaMajor Depressive Disorder (MDD)Bipolar Disorder+1 more
Second Affiliated Hospital, School of Medicine, Zhejiang University320 enrolled1 locationNCT07479758
Recruiting
Not Applicable

Group-based Stabilization and Skill Training for Patients With Lasting Posttraumatic Reactions in Mental Health Care

Stress Disorders, Post-TraumaticMental DisordersTrauma and Stressor Related Disorders
St. Olavs Hospital160 enrolled1 locationNCT03887559
Recruiting

KIDSHEART AND BRAIN : Early EEG Surgery Congenital Heart Disease Predict Onset of Neurodevelopmental Disorders

Neurodevelopmental DisordersCongenital Cardiomyopathy
University Hospital, Lille50 enrolled1 locationNCT05658965
Recruiting
Not Applicable

Study to Evaluate the Efficacy and Safety of ATNC-MDD V1(TMS With Cognitive Training) in Mild Alzheimer's Dementia

DementiaBrain DiseasesCentral Nervous System Diseases+5 more
Advanced Technology & Communications180 enrolled11 locationsNCT06088121