Mental Disorder Clinical Trials

172 recruitingLast updated: July 17, 2026

There are 172 actively recruiting mental disorder clinical trials across 39 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1. Top locations include Paris, France, Los Angeles, California, United States, Montreal, Quebec, Canada. Updated daily from ClinicalTrials.gov.


Mental Disorder Trials at a Glance

172 actively recruiting trials for mental disorder are listed on ClinicalTrialsFinder across 6 cities in 39 countries. The largest study group is Not Applicable with 90 trials, with the heaviest enrollment activity in Paris, Los Angeles, and Montreal. Lead sponsors running mental disorder studies include Chinese University of Hong Kong, Centre Hospitalier St Anne, and Hôpital le Vinatier.

Browse mental disorder trials by phase

Treatments under study

About Mental Disorder Clinical Trials

Looking for clinical trials for Mental Disorder? There are currently 30 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mental Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mental Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 172 trials

Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting
Not Applicable

Evaluation of Effectiveness of Child-oriented Goal-setting in Paediatric Rehabilitation (the ENGAGE Approach)

Cerebral PalsyAutism Spectrum DisorderNeurodevelopmental Disorders
University of Alberta96 enrolled6 locationsNCT04096430
Recruiting

The Effect of Comorbid Alcohol/Substance Use

SchizophreniaSubstance Use DisordersAlcohol Use Disorder+4 more
Abant Izzet Baysal University297 enrolled1 locationNCT07692984
Recruiting
Phase 2

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting

Natural History Study of GEMIN-5 Related Neurodevelopmental Disorder

Neurodevelopmental DisordersSMN Complex ProteinsGEMIN5 Protein, Human
University of Pittsburgh500 enrolled1 locationNCT06776341
Recruiting

Characterization and Support of Neurodevelopmental Disorders Associated With Congenital Cardiac malfoRmations - Neonatal

Neurodevelopmental DisorderHeart Disease Congenital
Nantes University Hospital450 enrolled8 locationsNCT06690151
Recruiting

Adolescent Psychiatry Inpatients: Self-reported Parent-adolescent Communication Quality and Treatment Outcome

AnxietyMental Disorder in AdolescenceDepression in Adolescence
Universitätsklinikum Hamburg-Eppendorf60 enrolled1 locationNCT06633458
Recruiting
Phase 3

Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder

GRIN-related Neurodevelopmental Disorder
GRIN Therapeutics, Inc.100 enrolled33 locationsNCT07224581
Recruiting

Rett Syndrome Registry

Genetic DiseaseNeurologic DisorderNervous System Diseases+7 more
International Rett Syndrome Foundation3,000 enrolled19 locationsNCT05432349
Recruiting
Not Applicable

Transcriptomic Approach for the Identification and Prioritization of Genome Variants in Neurodevelopmental Disorders With Malformation

Neurodevelopmental Disorders and Developmental Abnormalities
University Hospital, Angers58 enrolled7 locationsNCT06762678
Recruiting

Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders

SleepNeurodevelopmental DisorderNeurological Disorder+1 more
National Institute of Mental Health (NIMH)1,000 enrolled1 locationNCT01778504
Recruiting
Not Applicable

The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services

Cardiac conditionsCancerConnective Tissue Diseases+4 more
Unity Health Toronto170 enrolled3 locationsNCT06455384
Recruiting
Phase 2Phase 3

Virtual Menstrual Pain Approaches in Females

Digital HealthAcupressureMetabolomics+5 more
Nanyang Technological University145 enrolled1 locationNCT07497711
Recruiting
Not Applicable

Stimulation-Induced Changes in Fronto-Limbic Network

EpilepsyMental Disorders
University of Alabama at Birmingham30 enrolled1 locationNCT05854160
Recruiting

Platform for the Prospective Mother-child Study of the Determinants of Neurodevelopmental Disorders

Autism Spectrum DisorderNeurodevelopmental Disorders
University Hospital, Montpellier7,320 enrolled1 locationNCT05681923
Recruiting

Individual Neurophysiological Sensory Profiles in People With and Without Neurodevelopmental Disorders

Neurodevelopmental Disorders
University Hospital, Tours200 enrolled1 locationNCT07542977
Recruiting
Not Applicable

Homelessness and Prevalence of Neurodevelopmental Disorders

Neurodevelopmental Disorders
Hôpital le Vinatier150 enrolled1 locationNCT06869915
Recruiting
Not Applicable

Implementation of REFOCUS Training Program in Mental Health Services

Mental Disorders
Hôpital le Vinatier760 enrolled1 locationNCT05824234
Recruiting
Not Applicable

Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function

PsychopathologyAnxiety DisordersMental Disorders+3 more
Northwestern University500 enrolled1 locationNCT07641244
Recruiting

Neuraxial Labor Analgesia and Offspring Neurodevelopment

Pregnant womenNeurodevelopmental DisordersLabor Pain+2 more
Dong-Xin Wang4,645 enrolled2 locationsNCT04964206