Mental Disorder Clinical Trials

11 recruiting

Frequently Asked Questions

Common questions about Mental Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 41 trials

Recruiting

Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment Outcomes of Severe Mental Disorders

SchizophreniaMajor Depressive Disorder (MDD)Bipolar Disorder+1 more
Second Affiliated Hospital, School of Medicine, Zhejiang University320 enrolled1 locationNCT07479758
Recruiting

Psychiatric Multi-omics and Neuroimaging Project

Healthy ControlMental Disorders
mingjun Zhong1,899 enrolled1 locationNCT06580860
Recruiting
Phase 3

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

DementiaBrain DiseasesCentral Nervous System Diseases+6 more
Eli Lilly and Company1,500 enrolled141 locationsNCT05508789
Recruiting
Not Applicable

CongenItal Naevus Cohort for Longitudinal Evaluation

NaeviNeurodevelopmental DisorderCongenital Nevus
Nantes University Hospital819 enrolled16 locationsNCT06828822
Recruiting
Not Applicable

Stimulation-Induced Changes in Fronto-Limbic Network

EpilepsyMental Disorders
University of Alabama at Birmingham30 enrolled1 locationNCT05854160
Recruiting
Not Applicable

Brain Stimulation to the Hippocampus in Schizophrenia

Schizophrenia DisordersMental DisorderPsychotic Disorder
Stanford University60 enrolled1 locationNCT07010614
Recruiting
Not Applicable

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

Depression - Major Depressive DisorderMental DisorderCannabis Use Disorder
Massachusetts General Hospital80 enrolled1 locationNCT06878859
Recruiting
Not Applicable

Physical Activity and Community EmPOWERment Project

Williams SyndromeWAGR SyndromePrader-Willi Syndrome+10 more
University of North Carolina, Chapel Hill376 enrolled2 locationsNCT06740162
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting
Not Applicable

Effectiveness of a Pragmatic, Metabolic Care Clinic for Patients With Severe Mental Illness - The Meta Care Clinic

Bipolar DisorderSevere Mental DisorderSchizophrenia Spectrum and Other Psychotic Disorders+2 more
Bjorn H. Ebdrup84 enrolled1 locationNCT06624462
Recruiting
Phase 2

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Not Applicable

Going to Altitude With Anxious-depressive Symptoms

HypoxiaMental Disorder
Universitaet Innsbruck68 enrolled1 locationNCT05323864
Recruiting
Not Applicable

PTSD Treatment for Veterans With Serious Mental Illness to Improve Functional Outcomes

Stress Disorders, Post-Traumatic; Mental Disorders
VA Office of Research and Development48 enrolled1 locationNCT05674617
Recruiting

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

Cognitive ImpairmentDementiaCognitive Dysfunction+7 more
Mclean Hospital40 enrolled1 locationNCT05245903
Recruiting
Not Applicable

Study to Evaluate the Efficacy and Safety of ATNC-MDD V1(TMS With Cognitive Training) in Mild Alzheimer's Dementia

DementiaBrain DiseasesCentral Nervous System Diseases+5 more
Advanced Technology & Communications158 enrolled11 locationsNCT06088121
Recruiting
Not Applicable

The Effectiveness of Psychological Interventions for Common Mental Disorders

Common Mental Disorders and/or Stress Related Symptoms
University of Copenhagen308 enrolled1 locationNCT06916429
Recruiting
Not Applicable

Norwegian Mental Illness Heart Health Study

Severe Mental DisorderMetabolic Syndrome (MetS)Severe Mental Illness+5 more
Madeleine Elisabeth Angelsen70 enrolled1 locationNCT07085923
Recruiting

PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability

Pediatric ALLNeurodevelopmental DisordersInfant Development
University of Pennsylvania1,700 enrolled1 locationNCT04321200
Recruiting
Not Applicable

ACT for HIV-Positive Men

StressAnxietyMental Disorder+1 more
University of Alabama at Birmingham24 enrolled1 locationNCT06625437
Recruiting
Not Applicable

Pharmacogenomics-Supported Psychotropic Prescribing Trial

Adverse Drug Reaction (ADR)EffectivenessMental Disorder+1 more
University of Manitoba200 enrolled2 locationsNCT06929533