RecruitingPhase 1NCT07501117

Neoadjuvant Immunotherapy for Patients With High-risk Eye Melanoma

Neoadjuvant Ipilimumab and Nivolumab for Patients With High-risk Uveal Melanoma


Sponsor

Inge Marie Svane

Enrollment

15 participants

Start Date

Jun 29, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to investigate the safety and feasibility of neoadjuvant immunotherapy for patients with high-risk uveal melanoma. The main question is: \- Is neoadjuvant treatment with nivolumab and ipilimumab safe and feasible for patientt with high-riks uveal melanoma? In addition pathological response, distant metastases-free survival, overall survival and immunological changes in the tumor microenviroenment after therapy will be assesed.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Nivolumab & Ipilimumab for people with uveal melanoma. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNivolumab & Ipilimumab

Nivolumab 3 mg/kg Ipilimumab 1 mg/kg


Locations(1)

National Center for Cancer Immune Therapy, Department of Oncology, Herlev Hospital

Herlev, Herlev, Denmark

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NCT07501117


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