RecruitingNot ApplicableNCT07506239

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

PNOC042: A Phase 2, Multi-institutional Trial, Evaluating the Efficacy of Laser Interstitial Thermal Therapy (LITT) in Children, Adolescents and Young Adults With Recurrent or Progressive Low-grade Gliomas (LGG)


Sponsor

University of California, San Francisco

Enrollment

40 participants

Start Date

Mar 25, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to evaluate the efficacy of Laser Interstitial Thermal Therapy (LITT) in treating recurrent or progressive, low-grade gliomas (LGG) in pediatric, adolescent and young adult patients.


Eligibility

Min Age: 2 YearsMax Age: 25 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Laser Interstitial Thermal Therapy (LITT), a procedure called Magnetic resonance imaging (MRI), and others for people with low grade glioma of brain, low-grade glioma, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 2 Years to 25 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICELaser Interstitial Thermal Therapy (LITT)

Perform ablation using LITT

PROCEDUREMagnetic resonance imaging (MRI)

Undergo single imaging procedure

OTHERQuestionnaires

Participants will complete questionnaires


Locations(1)

University of California, San Francisco

San Francisco, California, United States

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NCT07506239


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