Comparison of PRESBYOND Laser Blended Vision and Conventional Monovision LASIK in Individuals With Presbyopia: A Randomized Clinical Study
Zhongshan Ophthalmic Center, Sun Yat-sen University
100 participants
May 12, 2026
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to learn if laser blended vision (LBV) works better than traditional monovision LASIK to correct presbyopia in adults aged 40 to 55 years. Presbyopia is an age-related condition that makes it hard to see things up close. The study will also evaluate the safety of both procedures. The main questions it aims to answer are: Does LBV improve distance, intermediate, and near vision at the same time after surgery? Is LBV as safe as traditional monovision LASIK? Researchers will compare laser blended vision to traditional monovision LASIK to see if LBV provides better overall vision after surgery. Participants will: Be randomly assigned to receive either laser blended vision or traditional monovision LASIK Have standard eye examinations before surgery Undergo LASIK surgery using the assigned method Return for follow-up visits at 1 week, 1 month, 3 months, and 6 months after surgery Complete vision tests and questionnaires about visual quality and satisfaction
Eligibility
Inclusion Criteria6
- Adults aged 40 to 55 years with presbyopia
- Suitable candidates for LASIK surgery based on clinical evaluation
- Stable refractive status for at least 1 year
- Best corrected distance visual acuity within normal range
- Willing and able to provide written informed consent
- Willing to comply with study visits and follow-up
Exclusion Criteria7
- Previous ocular surgery
- Corneal disease or abnormal corneal condition that may affect safety
- Significant ocular disease affecting visual function
- Severe dry eye or other ocular surface disorders
- Systemic disease that may affect study participation
- Inability to tolerate monovision or anisometropia
- Any condition that the investigator considers unsuitable for the study
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Interventions
Laser blended vision LASIK is a refractive surgery technique for presbyopia correction. The dominant eye is corrected for distance vision, and the non-dominant eye is adjusted to mild myopia to improve near vision using a laser blended vision design.
Monovision LASIK is a refractive surgery technique in which the dominant eye is corrected for distance vision and the non-dominant eye is corrected for near vision to improve presbyopia.
Locations(1)
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NCT07512089