Presbyopia Clinical Trials

22 recruitingLast updated: June 18, 2026

There are 22 actively recruiting presbyopia clinical trials across 10 countries. Studies span Not Applicable, Phase 4, Phase 2, Phase 3. Top locations include Berkeley, California, United States, Memphis, Tennessee, United States, Bala-Cynwyd, Pennsylvania, United States. Updated daily from ClinicalTrials.gov.


Presbyopia Trials at a Glance

22 actively recruiting trials for presbyopia are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 12 trials, with the heaviest enrollment activity in Berkeley, Memphis, and Bala-Cynwyd. Lead sponsors running presbyopia studies include CooperVision International Limited (CVIL), Alcon Research, and Southern College of Optometry.

Browse presbyopia trials by phase

Treatments under study

About Presbyopia Clinical Trials

Looking for clinical trials for Presbyopia? There are currently 32 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Presbyopia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Presbyopia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Not Applicable

Contralateral Claims Study of Clareon Vivity Pro

PresbyopiaAphakia
Alcon Research231 enrolled9 locationsNCT07484191
Recruiting
Not Applicable

Refitting Satisfied INFUSE One-Day Multifocal Wearers to DAILIES TOTAL1 Multifocal Contact Lenses

PresbyopiaContact Lens Comfort and Successful Refitting
Gordon Schanzlin New Vision30 enrolled1 locationNCT07638943
Recruiting
Not Applicable

Refocus VisAbility™ Micro Insert System Pre-market Clinical Trial

Presbyopia
Refocus Group, Inc.33 enrolled1 locationNCT07637500
Recruiting
Not Applicable

Clinical Performance of Verofilcon A Toric Contact Lenses

PresbyopiaContact Lenses
Southern College of Optometry32 enrolled1 locationNCT07586982
Recruiting
Not Applicable

Performance of Two Daily Disposable Multifocal Contact Lenses

Presbyopia
CooperVision International Limited (CVIL)35 enrolled1 locationNCT07444658
Recruiting
Not Applicable

Presbyopic Wear Experience With Multifocal Lenses Compared to Single Vision Lenses and Reading Glasses

PresbyopiaPresbyopia Correction
Ohio State University30 enrolled1 locationNCT07218731
Recruiting

Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections With EDOF IOLs

Presbyopia
Democritus University of Thrace100 enrolled1 locationNCT07077967
Recruiting

Comfort and Vision With TOTAL30 Multifocal Lenses

MyopiaAstigmatismPresbyopia
Scripps Poway Eyecare and Optometry36 enrolled1 locationNCT07284966
Recruiting

IC-8 Apthera IOL New Enrollment Post Approval Study

PresbyopiaCataractPosterior Capsule Opacification
Bausch & Lomb Incorporated435 enrolled14 locationsNCT06060041
Recruiting
Not Applicable

A Planned Study at Multiple Sites is Being Done to Compare the Results of Two Types of Trifocal Toric Intraocular Lenses Used in Cataract Surgery

AstigmatismCataractPresbyopia Correction
Biotech Healthcare Holding Gmbh138 enrolled6 locationsNCT07232615
Recruiting
Not Applicable

Post Market Clinical Evaluation of Clareon PanOptix Pro and Clareon PanOptix Pro Toric IOLs

PresbyopiaAphakia
Alcon Research120 enrolled5 locationsNCT07161635
Recruiting

North American Comfilcon A Clinical Study

AstigmatismPresbyopiaAmetropia
CooperVision International Limited (CVIL)182 enrolled4 locationsNCT06902584
Recruiting

"My Eyes, My Light": Amar Chokh, Amar Alo

MyopiaDiabetic Retinopathy (DR)Presbyopia+6 more
Data Yakka, Inc.20,000 enrolled1 locationNCT07135570
Recruiting
Not Applicable

Clinical Applications of Advanced Ophthalmic Imaging

DementiaMultiple SclerosisMyopia+3 more
University of Miami5,000 enrolled1 locationNCT03135327
Recruiting
Phase 4

Quality of Life in Presbyopic Patients Who Are Treated With Qlosi

Dry EyePresbyopiaGlasses
Southern College of Optometry36 enrolled2 locationsNCT07113210
Recruiting
Not Applicable

Head-to-Head Comparison of Five Enhanced Depth of Focus IOLs and One Monofocal IOL

Cataract and IOL SurgeryPresbyopia CorrectionIOL Implantation+1 more
Augenklinik Ahaus G + H GmbH & Co. KG180 enrolled1 locationNCT07051720
Recruiting

Can eye drops safely replace reading glasses in older adults? A short-term study.

Retinal ischemiaPresbyopia
The University of Auckland24 enrolled1 locationACTRN12625000542493
Recruiting
Phase 2

Efficacy and Safety of BRIMOCHOL PF and CARBACHOL PF in Chinese Presbyopia Patients

Presbyopia
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.119 enrolled1 locationNCT06948357
Recruiting
Not Applicable

A Clinical Comparison of Proclear® 1 Day Multifocal and Clariti® 1 Day Multifocal 3 Add

MyopiaPresbyopiaHyperopia
CooperVision International Limited (CVIL)66 enrolled1 locationNCT06869044
Recruiting
Phase 3

Phase III Presbyopia Correction Using the VIS Opti-K™ System

Presbyopia
VIS, Inc.75 enrolled4 locationsNCT06487897