RecruitingPhase 3NCT07516132

Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study

A Phase 3b, Multicenter, Open-Label, Extension Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study

Sponsor

Ocular Therapeutix, Inc.

Enrollment

850 participants

Start Date

Apr 27, 2026

Study Type

INTERVENTIONAL

Conditions

Neovascular Age-Related Macular Degeneration (nAMD)

Summary

Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants with Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study

Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called OTX-TKI for people with neovascular age-related macular degeneration (namd). The study is currently recruiting participants at 8 locations. People eligible for this study include aged 50 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGOTX-TKI

Intravitreal Injection of OTX-TKI

Locations(8)

California Retina Consultants (CRC)

Bakersfield, California, United States

California Retina Consultants (CRC)

Santa Barbara, California, United States

Retina Group of New England

Waterford, Connecticut, United States

Retina Group of Florida - Fort Lauderdale

Fort Lauderdale, Florida, United States

Cumberland Valley Retina Associates

Hagerstown, Maryland, United States

Mid Atlantic Retina Specialists

Hagerstown, Maryland, United States

Palmetto Retina Center

West Columbia, South Carolina, United States

Austin Retina Associates

Austin, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT07516132

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