RecruitingNCT07522580

Fluid-responsiveness Assessment Simplified by Electric Cardiometry in Children


Sponsor

University Hospital, Bordeaux

Enrollment

42 participants

Start Date

Jul 22, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

In this study of diagnostic accuracy, the investigators aim to validate a faster, simpler, and noninvasive test of fluid-responsiveness in critically ill children. This test is based on an assessment of the hemodynamic effects of a standardized abdominal compression, using electrical cardiometry. This would help physicians to identify more easily which patient could benefit from a volume expansion, thus avoiding a potentially useless or even dangerous fluid expansion that could lead to fluid overload. To this end, the diagnostic accuracy of electrical cardiometry-based stroke volume (SV) variation induced by a standardized abdominal compression to predict fluid responsiveness (define as a 15% increase in echocardiographically measured SV after volume expansion) will be measured.


Eligibility

Min Age: 0 DaysMax Age: 8 Years

Inclusion Criteria4

  • Age less than or equal to 8 years old
  • Hospitalization in a pediatric intensive care unit
  • Prescription by the attending physician of a fluid expansion of 10ml/kg
  • Use of a non-invasive cardiac output monitoring device (electrical cardiometry) as part of routine care

Exclusion Criteria6

  • Patient less than 37 weeks' corrected gestational age
  • Hemodynamic instability making the delay necessary for any test dangerous
  • Supine position contraindicated or deleterious
  • Impairment of echocardiographic acoustic window or restless patient making ultrasonography impossible
  • Opposition to participate expressed by the patient or by a parent or legal guardian
  • Intra-abdominal hypertension, painful abdominal palpation or abdominal surgery in the last 15 days

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Interventions

DIAGNOSTIC_TESTvalidation a test of fluid-responsiveness in critically ill children

This test is based on an assessment of the hemodynamic effects of a standardized abdominal compression, using electrical cardiometry.


Locations(4)

Hôpital Marie Lannelongue

Le Plessis-Robinson, France, France

Hôpital Arnaud de Villeneuve - CHU de Montpellier

Montpellier, France, France

Hôpital mère-enfant - CHU de Nantes

Nantes, France, France

Hôpital Cardiologique Haut Lévêque - CHU de Bordeaux

Pessac, France, France

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NCT07522580


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