Circulatory Failure Clinical Trials

11 recruitingLast updated: June 18, 2026

There are 11 actively recruiting circulatory failure clinical trials across 9 countries. Studies span Not Applicable, Phase 4. Top locations include Pessac, France, France, Paris, France, Nantes, France, France. Updated daily from ClinicalTrials.gov.


Circulatory Failure Trials at a Glance

11 actively recruiting trials for circulatory failure are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 2 trials, with the heaviest enrollment activity in Pessac, Paris, and Nantes. Lead sponsors running circulatory failure studies include University Hospital, Bordeaux, ETH Zurich, and Assistance Publique - Hôpitaux de Paris.

Browse circulatory failure trials by phase

Treatments under study

About Circulatory Failure Clinical Trials

Looking for clinical trials for Circulatory Failure? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Circulatory Failure trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Circulatory Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting

ICU Background Early Awareness for Critical deterioratiON

MortalityRespiratory FailureOrgan Failure, Multiple+2 more
ETH Zurich1,962 enrolled1 locationNCT07119411
Recruiting

Prediction of Fluid Responsiveness Using the Femoral Vein-to-Artery Diameter Ratio

Acute circulatory failureShockFluid responsiveness
Istanbul University - Cerrahpasa100 enrolled1 locationNCT07546656
Recruiting
Phase 4

Hydrocortisone Therapy Optimization During Hypothermia Treatment in Asphyxiated Neonates

HypotensionAsphyxiaCirculatory Failure Neonatal+1 more
Semmelweis University50 enrolled1 locationNCT05836610
Recruiting

Fluid-responsiveness Assessment Simplified by Electric Cardiometry in Children

Circulatory FailureFluid TherapyShock State
University Hospital, Bordeaux42 enrolled4 locationsNCT07522580
Recruiting
Not Applicable

Fluid-responsiveness in Children Ventilated With LOW Tidal Volume - The FLOW Study.

Circulatory Failure (Shock)
University Hospital, Bordeaux60 enrolled6 locationsNCT07494643
Recruiting

Metabolic Fluid Responsiveness in Children

Circulatory Failure / Shock StateFluid Therapy
University Hospital, Bordeaux110 enrolled8 locationsNCT07255469
Recruiting

Peripheral Tissue Perfusion in Intensive Care

Acute circulatory failure
Assistance Publique - Hôpitaux de Paris180 enrolled1 locationNCT06384287
Recruiting
Phase 4

Comparing Anticoagulation Strategies Using UFH, Argatroban and LMWH for ECMO Support

BleedingThromboembolismRespiratory Insufficiency+1 more
Medical University of Vienna90 enrolled1 locationNCT06442267
Recruiting

Monitoring of Cerebral Blood Flow in Patients on Extracorporeal Membrane Oxygenation

Extracorporeal Membrane Oxygenation ComplicationCerebral Circulatory Failure
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)15 enrolled1 locationNCT05303363
Recruiting
Not Applicable

the Impact of Manual or Mechanical Ways to Perform PLR on the Accuracy of Evaluation of Fluid Responsiveness

Circulatory Failure
Southeast University, China60 enrolled1 locationNCT06285331
Recruiting

Validation of a novel algorithm for dynamic assessment of fluid challenge: a multicentric study

Acute circulatory failureHypoperfusionHypotension
antonio messina82 enrolled3 locationsACTRN12617000076370