RecruitingPhase 1NCT07525791

A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body Weight

An Investigation of the Effect of NNC0662-0419 on Pharmacokinetics of an Oral Combination Contraceptive (Ethinylestradiol and Levonorgestrel) and Gastric Emptying in Women of Non-childbearing Potential With Overweight or Obesity


Sponsor

Novo Nordisk A/S

Enrollment

45 participants

Start Date

Apr 7, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this clinical study is to find out if NNC0662-0419 is safe and effective to be taken together with other medicines, like birth control pills, and emptying of the stomach in women not able to become pregnant living with overweight or obesity. There are 3 study treatments in this study, participants will get all of the treatments, NNC0662-0419 the treatment being tested, Altavera a type of birth control pill, Acetaminophen a common type of mild painkiller.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 64 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Acetaminophen, a drug called NNC0662-0419, and others for people with obesity and overweight. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years to 64 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNNC0662-0419

Once-weekly subcutaneous NNC0662-0419 will be administered using a pen injector

DRUGOral contraceptive

An oral contraceptive Altavera \[levonorgestrel (LN) 0.15 milligram (mg) and ethinyl estradiol (EE) 0.03 mg\] will be administered orally.

DRUGAcetaminophen

A single dose of acetaminophen will be administered orally.


Locations(1)

Altasciences Clinical Kansas, Inc.

Overland Park, Kansas, United States

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NCT07525791


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