RecruitingNCT07530718

Body Composition Outcomes in MS Patients

Outcome of Body Composition Assessment in Patients With Severe Obesity Undergoing Metabolic Surgery


Sponsor

Pennington Biomedical Research Center

Enrollment

20 participants

Start Date

Apr 14, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

Objectives The objective of this project is to generate pilot data substantiating our hypothesis that advanced body composition measurement tools will provide more accurate and clinically relevant data on the outcomes of metabolic surgery (MS) in patients with severe obesity compared to traditional methods. To achieve this objective, the investigators propose the following aims: Aim 1: Evaluate the effectiveness of different body composition measurement tools in assessing outcomes in patients with severe obesity undergoing MS. Aim 2: Assess the changes in body composition and muscle strength following MS. Aim 3: Compare body compositions changes between SG and RYGB patients.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Being either male or female
  • Being an adult greater or equal to 18 years of age
  • BMI ≥40 kg/m2
  • Weigh less than 440 pounds
  • Being willing to comply with the study procedures
  • Being scheduled for primary metabolic surgery (either Sleeve Gastrectomy or Roux-en-Y Gastric bypass)

Exclusion Criteria8

  • Previous bariatric surgery or other complex abdominal surgery
  • Poorly controlled medical or psychiatric disorders
  • For women in child-bearing ages, being pregnant or attempting to become pregnant or currently breastfeeding
  • Having metal-containing objects in their body that may cause artifact on MRI
  • Having medical implants such as a pacemaker or metal joint replacements
  • Having a body weight greater than 440 pounds
  • Comorbid conditions that may affect body composition measurements, such as advanced liver disease or severe cardiovascular disease.
  • Cannot understand risks, benefits, and compliance required to participate.

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Locations(2)

Pennington Biomedical Resarch Center

Baton Rouge, Louisiana, United States

Pennington Biomedical Research Center

Baton Rouge, Louisiana, United States

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NCT07530718


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