RecruitingNCT07579728

CALLY Index, Frailty and SOFA-2 for Mortality Prediction in Geriatric ICU Patients

Prognostic Value of CALLY Index, Frailty and SOFA-2 Score for Mortality in Geriatric Intensive Care Patients: A Prospective Cohort Study


Sponsor

Istanbul University - Cerrahpasa

Enrollment

100 participants

Start Date

Apr 30, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to evaluate the prognostic value of the C-reactive protein-albumin-lymphocyte (CALLY) index, Clinical Frailty Scale (CFS), and SOFA-2 score in predicting mortality among geriatric intensive care unit (ICU) patients. The primary outcome is ICU mortality. Secondary outcomes include 28-day mortality, ICU length of stay, duration of mechanical ventilation, need for renal replacement therapy, and vasopressor requirement. The study also investigates whether the combined use of these parameters improves predictive performance compared to conventional scoring systems such as APACHE II.


Eligibility

Min Age: 65 Years

Inclusion Criteria3

  • Age ≥65 years
  • Admission to the intensive care unit
  • Availability of required clinical and laboratory data within the first 24 hours of ICU admission

Exclusion Criteria3

  • Death within the first 24 hours after ICU admission
  • Missing key clinical or laboratory data
  • Terminal malignancy receiving palliative care

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Interventions

OTHERobservational study

No intervention is applied.This is an observational study in which patients receive standart clinical care.


Locations(1)

Başakşehir Çam and Sakura City Hospital

Istanbul, Turkey (Türkiye)

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NCT07579728


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