Mindfulness With Dual-Task Training in Post-Stroke Mild Cognitive Impairment
Mindfulness Combined With Dual-Task Training for Post-Stroke Mild Cognitive Impairment: A Randomized Controlled Trial
Nanjing Mingzhou Rehabilitation Hospital
60 participants
May 1, 2026
INTERVENTIONAL
Conditions
Summary
This study aims to investigate whether a combined intervention of mindfulness and dual-task training can improve cognitive function and physical performance in individuals with mild cognitive impairment after stroke.
Eligibility
Inclusion Criteria7
- Diagnosis of stroke confirmed by computed tomography (CT) or magnetic resonance imaging (MRI).
- Time since stroke onset ≥3 months and medically stable.
- Presence of mild cognitive impairment after stroke, defined by a Montreal - - Montreal Cognitive Assessment (MoCA) score < 26.
- Mini-Mental State Examination (MMSE) score ≥ 24.
- Ability to walk independently with or without an assistive device for at least 10 meters.
- Stable medication regimen for at least 4 weeks prior to enrollment.
- Ability to understand study instructions and provide written informed consent.
Exclusion Criteria7
- Severe aphasia, visual impairment, hearing impairment, or communication disorders that interfere with assessment or training participation.
- Severe depression or other major psychiatric disorders.
- Other neurological diseases affecting cognition or movement (e.g., Parkinson's disease, multiple sclerosis, traumatic brain injury).
- Severe musculoskeletal, cardiovascular, or systemic diseases that contraindicate exercise participation.
- Participation in other structured cognitive or rehabilitation intervention programs within the past 3 months.
- Unstable medical condition or recurrent stroke during the study period.
- Inability to safely complete the training protocol as determined by the study investigators.
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Interventions
Guided by a professional mindfulness instructor, participants engage in mindfulness meditation to enhance attention, emotional regulation, and cognitive readiness. The training includes breath awareness, body scan, and present-moment awareness, delivered through guided meditation.Other Name:
Dual-task training is a rehabilitation approach that targets cognitive-motor integration by requiring participants to perform a motor task and a cognitive task simultaneously. Examples include walking while performing mental calculations, memory tasks, or reaction-based exercises. The training is progressively adjusted by increasing task difficulty and cognitive load to improve attention allocation, executive function, and dual-task performance in daily activities.
Dual-task training is a rehabilitation approach that targets cognitive-motor integration by requiring participants to perform a motor task and a cognitive task simultaneously. Examples include walking while performing mental calculations, memory tasks, or reaction-based exercises. The training is progressively adjusted by increasing task difficulty and cognitive load to improve attention allocation, executive function, and dual-task performance in daily activities.
Health education is a non-exercise control intervention designed to provide participants with knowledge related to post-stroke health management. Topics include stroke recovery, healthy lifestyle behaviors, nutrition, medication adherence, daily activity management, and psychological well-being. The intervention is delivered through structured educational sessions or instructional materials and does not include active physical or cognitive training components.
Locations(1)
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NCT07603102