RecruitingPhase 2NCT07604974

A Study to Assess the Safety, Tolerability and Efficacy of ION775

A Phase 2, Open-label Trial Evaluating the Safety, Tolerability and Efficacy of ION775 in Adults With Hypertriglyceridemia

Sponsor

Ionis Pharmaceuticals, Inc.

Enrollment

72 participants

Start Date

May 12, 2026

Study Type

INTERVENTIONAL

Conditions

Hypertriglyceridemia Severe Hypertriglyceridemia

Summary

The main objective of this study is to evaluate the effect of ION775 on fasting triglyceride (TG) levels in participants with hypertriglyceridemia (HTG) and severe hypertriglyceridemia (sHTG).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called ION775 for people with hypertriglyceridemia and severe hypertriglyceridemia. The study is currently recruiting participants at 16 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGION775

ION775 will be administered by SC injection.

Locations(16)

Ionis Investigative Site

Lincoln, California, United States

Ionis Investigative Site

Aurora, Colorado, United States

Ionis Investigative Site

Boca Raton, Florida, United States

Ionis Investigative Site

Miami, Florida, United States

Ionis Investigative Site

Miramar, Florida, United States

Ionis Investigative Site

Columbus, Georgia, United States

Ionis Investigative Site

Louisville, Kentucky, United States

Ionis Investigative Site

Flint, Michigan, United States

Ionis Investigative Site

Munroe Falls, Ohio, United States

Ionis Investigative Site

Little River, South Carolina, United States

Ionis Investigative Site

Houston, Texas, United States

Ionis Investigative Site

Lampasas, Texas, United States

Ionis Investigative Site

McKinney, Texas, United States

Ionis Investigative Site

Mesquite, Texas, United States

Ionis Investigative Site

San Antonio, Texas, United States

Ionis Investigative Site

Québec, Canada

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07604974

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