Hypertriglyceridemia Clinical Trials

17 recruiting

Hypertriglyceridemia Trials at a Glance

19 actively recruiting trials for hypertriglyceridemia are listed on ClinicalTrialsFinder across 6 cities in 36 countries. The largest study group is Phase 2 with 6 trials, with the heaviest enrollment activity in Beijing, San Antonio, and Belo Horizonte. Lead sponsors running hypertriglyceridemia studies include Arrowhead Pharmaceuticals, Dhurakij Pundit University, and CRISPR Therapeutics AG.

Browse hypertriglyceridemia trials by phase

Treatments under study

About Hypertriglyceridemia Clinical Trials

Looking for clinical trials for Hypertriglyceridemia? There are currently 17 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hypertriglyceridemia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hypertriglyceridemia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Phase 1

Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia

HypercholesterolemiaHypertriglyceridemiaRefractory Hyperlipidemia
Verve Therapeutics, Inc.36 enrolled10 locationsNCT06451770
Recruiting
Phase 2

A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia

Severe Hypertriglyceridemia
Eli Lilly and Company60 enrolled40 locationsNCT07269210
Recruiting
Not Applicable

Effect of Consuming n-3 Polyunsaturated Fatty Acids Rich Foods on Triglyceride Concentration and Lipoprotein Composition

Hypertriglyceridemia
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran375 enrolled1 locationNCT07004777
Recruiting
Not Applicable

WB-EMS Effects on Cardiometabolic Risk Factors

Metabolic SyndromeHypertensionOverweight and Obesity+2 more
University of Erlangen-Nürnberg Medical School42 enrolled2 locationsNCT07406191
Recruiting
Phase 3

Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia

Hypertriglyceridemia
Arrowhead Pharmaceuticals869 enrolled238 locationsNCT06822790
Recruiting

Russian Extreme Hypertriglyceridemia Registry

Hypertriglyceridemia
Russian Cardiology Research and Production Center500 enrolled6 locationsNCT07508930
Recruiting
Phase 1

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

HypercholesterolaemiaMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG90 enrolled18 locationsNCT07491172
Recruiting
Phase 2

Phase II Clinical Trial Evaluating the Efficacy and Safety of HRS-7249 and SHR-1918 in Patients With Severe Hypertriglyceridemia at High Risk of Acute Pancreatitis

Severe Hypertriglyceridemia With a High Risk of Acute Pancreatitis
Fujian Shengdi Pharmaceutical Co., Ltd.108 enrolled1 locationNCT07308392
Recruiting
Phase 3

Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

Severe Hypertriglyceridemia
Arrowhead Pharmaceuticals288 enrolled61 locationsNCT06880770
Recruiting
Not Applicable

Adding Evolocumab to Conventional Lipid-lowering Therapy for Hypertriglyceridemia Induced Acute Pancreatitis

Hypertriglyceridemia Induced Acute Pancreatitis
General Hospital of Shenyang Military Region40 enrolled1 locationNCT07388420
Recruiting
Not Applicable

Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance Phenotypes

Insulin ResistanceHypertriglyceridemia
Yale University40 enrolled1 locationNCT05743868
Recruiting
Phase 1Phase 2

a Phase 1b/2a Study of JMT202 Injection in Participants With Hypertriglyceridemia

Hypertriglyceridemia
Shanghai JMT-Bio Inc.48 enrolled1 locationNCT07140809
Recruiting
Phase 2

A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol

Hypertriglyceridemia
Marea Therapeutics30 enrolled1 locationNCT07199309
Recruiting
Early Phase 1

Differential Thrombogenesis by EPA and DHA Mediated by HDL

HypertriglyceridemiaLipid Metabolism Disorders
The Miriam Hospital80 enrolled1 locationNCT06494488
Recruiting

Interest of High-speed Centrifugation for Measuring Anti-Xa Activity on Lipemic Plasma

Hypertriglyceridemia
University Hospital, Strasbourg, France150 enrolled1 locationNCT07200674
Recruiting
Phase 1

Safety Evaluation of Gene Therapy Drug in the Treatment of Primary Hypertriglyceridemic Patients With Recurrent Pancreatitis

Hypertriglyceridemia, Familial
GeneCradle Inc7 enrolled1 locationNCT05860569
Recruiting

Vitamin C Administration and Triglycerides Level in Critical Care Patients

Hypertriglyceridemia
Meir Medical Center2,000 enrolled1 locationNCT06206759
Recruiting
Phase 2

Phase 2a Study of Safety, Tolerability, and Efficacy of TLC-2716 in Subjects With Hypertriglyceridemia and NAFLD

Nonalcoholic Fatty Liver DiseaseHypertriglyceridemia
OrsoBio, Inc30 enrolled4 locationsNCT06564584
Recruiting
Phase 2Phase 3

Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal Women

DyslipidemiasPostmenopausal SymptomsHypercholesterolemia+3 more
Dhurakij Pundit University10 enrolled1 locationNCT06220266