RecruitingPhase 4NCT07611890

Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial

Comparison of Intravenous Dexmedetomidine and Lignocaine in Reducing Hemodynamic Responses During Laryngoscopy and Endotracheal Intubation In Patients Undergoing Cardiac Surgery at Rawalpindi Institute Of Cardiology- A Randomized Controlled Trial


Sponsor

Rawalpindi Institute of Cardiology

Enrollment

70 participants

Start Date

May 21, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

After confirming eligibility, written informed consent will be obtained by a trained team member who is not involved in assigning treatment or giving the study medication. Each participant will receive a unique study number to protect privacy. Participants will be randomly assigned to receive one of the study medications using a chance-based method.The study medication will be administered through a vein before placement of the breathing tube. Blood pressure and pulse rate will be measured before the procedure and at several time points after the breathing tube is inserted.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called IV Lignocaine and a drug called IV dexmedetomidine for people with dexmedetomidine, laryngoscopic stress response, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGIV dexmedetomidine

0.5 Mcg/kg of Dexmedetomidine will be given 10 minutes before laryngoscopy

DRUGIV Lignocaine

Patients will be given 1.5 mg/kg of Lignocaine 3 minutes before laryngoscopy


Locations(1)

Rawalpindi Institute of Cardiology

Rawalpindi, Punjab Province, Pakistan

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NCT07611890


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