RecruitingNCT07617974
Natural History of Atrial Fibrillation-Induced Tricuspid Valve Remodeling in the Absence of Significant Tricuspid Regurgitation: A Three-Dimensional Echocardiographic Study
Natural History of Atrial Fibrillation-Induced Tricuspid Valve Remodeling in the Absence of Significant Tricuspid Regurgitation: A Three-Dimensional Echocardiographic Study (TRICUSPID-AF)
Sponsor
Centro Cardiologico Monzino
Enrollment
66 participants
Start Date
May 4, 2026
Study Type
OBSERVATIONAL
Conditions
Summary
This is a prospective, observational, multicenter study aimed at characterizing tricuspid valve remodeling in patients with atrial fibrillation (AF) without significant tricuspid regurgitation (TR), in relation to AF burden progression.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Consecutive patients with atrial fibrillation (paroxysmal or persistent) undergoing transthoracic echocardiography (TTE) prior to AF ablation with acquisition of a 3D TV dataset.
- Eligible for enrollment in the control group will be:
- all consecutive patients with structurally normal hearts and no history of AF or;
- moderate atrial functional tricuspid regurgitation and AF, in the absence of significant left-sided valvular disease or prior valvular surgery.
Exclusion Criteria5
- Moderate or greater TR assessed using a multiparametric approach;
- Arrhythmias other than AF;
- Prior AF ablations;
- Rapid ventricular response (average HR >110 bpm) during baseline TTE;
- Inadequate image quality
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07617974
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