Tricuspid Regurgitation (TR) Clinical Trials

8 recruitingLast updated: July 25, 2026

There are 8 actively recruiting tricuspid regurgitation (tr) clinical trials across 8 countries. Studies span Not Applicable. Top locations include Asunción, Paraguay, Barcelona, Spain, Chicago, Illinois, United States. Updated daily from ClinicalTrials.gov.


Tricuspid Regurgitation (TR) Trials at a Glance

8 actively recruiting trials for tricuspid regurgitation (tr) are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Asunción, Barcelona, and Chicago. Lead sponsors running tricuspid regurgitation (tr) studies include Centro Cardiologico Monzino, Columbia University, and Abbott Medical Devices.

Browse tricuspid regurgitation (tr) trials by phase

About Tricuspid Regurgitation (TR) Clinical Trials

Looking for clinical trials for Tricuspid Regurgitation (TR)? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Tricuspid Regurgitation (TR) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Tricuspid Regurgitation (TR) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting

A Post-Market Assessment of the Safety and Performance of the TriClip™ System

Tricuspid Regurgitation (TR)
Abbott Medical Devices1,000 enrolled4 locationsNCT07586995
Recruiting

Efficacy of Early Rhythm Control in AF With TR Patients

Atrial Fibrillation (AF)Tricuspid Regurgitation (TR)
Samsung Medical Center5,800 enrolled1 locationNCT07607093
Recruiting

Natural History of Atrial Fibrillation-Induced Tricuspid Valve Remodeling in the Absence of Significant Tricuspid Regurgitation: A Three-Dimensional Echocardiographic Study

Atrial Fibrillation (AF)Tricuspid Regurgitation (TR)
Centro Cardiologico Monzino66 enrolled1 locationNCT07617974
Recruiting

DELINEATE-Prospective

Valvular Heart DiseaseValve Disease, AorticAortic Stenosis+3 more
Columbia University50 enrolled1 locationNCT07197736
Recruiting
Not Applicable

Robotic Transjugular Transcatheter Tricuspid Valve Replacement

Tricuspid Regurgitation (TR)Transcatheter Valve ReplacementValvular Heart Diseases
Prince of Wales Hospital, Shatin, Hong Kong10 enrolled1 locationNCT07516145
Recruiting
Not Applicable

Safety and Feasibility Study: Transcatheter Valve Repair in Severe Symptomatic Functional Tricuspid Regurgitation

Tricuspid RegurgitationTricuspid Regurgitation (TR)Tricuspid Regurgitation Functional
Tangent Cardiovascular Inc.25 enrolled1 locationNCT07140562
Recruiting
Not Applicable

Early Feasibility of 'Pivot Extend' for Tricuspid Regurgitation Treatment

Tricuspid Regurgitation (TR)
Tau-MEDICAL Co., Ltd.7 enrolled3 locationsNCT06877520
Recruiting

Pacemaker Implantation Following Transcatheter Tricuspid Valve Replacement

AV Block CompleteTricuspid Regurgitation (TR)
Deutsches Herzzentrum Muenchen25 enrolled1 locationNCT06814574