RecruitingPhase 1NCT07619287

An Investigational Study of BG-75202 Alone and in Combination With Other Agents in Patients With Myeloid Malignancies

A Phase 1a/1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of BG-75202, Alone and in Combination With Other Agents, in Patients With Myeloid Malignancies


Sponsor

BeOne Medicines

Enrollment

118 participants

Start Date

Jun 23, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of BG-75202 (KAT6A/B inhibitor) alone and in combination with other agents in patients with myeloid malignancies.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called BG-75202 and a drug called Hypomethylation Agent (HMA) for people with myeloid malignancy. The study is currently recruiting participants at 4 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGBG-75202

Administered orally

DRUGHypomethylation Agent (HMA)

Administered Intravenous (IV) or Subcutaneous (SC)


Locations(4)

Icon Cancer Centre Kurralta Park

Kurralta Park, South Australia, Australia

Linear Clinical Research

Nedlands, Western Australia, Australia

Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciencestuanbo Branch

Tianjin, Tianjin Municipality, China

Auckland City Hospital

Auckland, New Zealand

View Full Details on ClinicalTrials.gov

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NCT07619287


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