RecruitingPhase 3NCT07623668

Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research

A Randomized, Double-masked, Placebo-controlled Study Assessing the Efficacy and Safety of Privosegtor (OCS-05) in Patients With Optic Neuritis (ON)


Sponsor

Oculis

Enrollment

210 participants

Start Date

May 28, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to evaluate the safety and efficacy of privosegtor, a neuroprotective candidate, in patients diagnosed with optic neuritis (ON). Researchers will compare privosegtor and the standard of care (methylprednisolone) to a placebo and standard of care (methylprednisolone).


Eligibility

Min Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Methylprednisolone, Placebo, and others for people with optic neuritis. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPrivosegtor

Privosegtor (OCS-05) 3 mg/kg/day IV for 5 treatment days

DRUGMethylprednisolone

Methylprednisolone 1 g/day IV for 5 treatment days

OTHERPlacebo

0.9% sodium chloride (NaCl) solution IV for 5 treatment days


Locations(1)

Neuro-Eye Clinical Trials

Houston, Texas, United States

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NCT07623668


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