Optic Neuritis Clinical Trials

9 recruiting

Optic Neuritis Trials at a Glance

9 actively recruiting trials for optic neuritis are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Lille, Boston, and Baltimore. Lead sponsors running optic neuritis studies include University Hospital, Lille, Mayo Clinic, and First Affiliated Hospital of Guangxi Medical University.

Browse optic neuritis trials by phase

Treatments under study

About Optic Neuritis Clinical Trials

Looking for clinical trials for Optic Neuritis? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Optic Neuritis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Optic Neuritis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Phase 3

Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

Optic NeuritisMyelitisMyelitis, Transverse
Mayo Clinic382 enrolled24 locationsNCT07100990
Recruiting
Phase 2

Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)

Optic Neuritis
University of California, San Francisco90 enrolled1 locationNCT02521311
Recruiting
Phase 2

Efgartigimod for the Treatment of Acute Optic Neuritis

Optic Neuritis
Anastasia Vishnevetsky, MD, MPH20 enrolled2 locationsNCT06453694
Recruiting

VIsual Pathways Model in Neuro-inflammatory Disorders

Optic Neuritis
University Hospital, Lille100 enrolled1 locationNCT05487989
Recruiting
Not Applicable

Retinal Neuro-vascular Coupling in Patients With Multiple Sclerosis

Optic NeuritisMultiple Sclerosis, Relapsing-Remitting
Medical University of Vienna50 enrolled1 locationNCT03401879
Recruiting
Not Applicable

Edaravone in the Treatment of Optic Neuritis

Optic Neuritis
First Affiliated Hospital of Guangxi Medical University50 enrolled1 locationNCT05540262
Recruiting
Not Applicable

Visual (Path)Ways in Multiple Sclerosis - Part II

Multiple Sclerosis, Optic Neuritis, Demyelinating Disease
University Hospital, Lille64 enrolled1 locationNCT06776224
Recruiting

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Multiple SclerosisOptic NeuritisTransverse Myelitis+15 more
University of Bern500 enrolled13 locationsNCT05017142
Recruiting
Not Applicable

Light Stimulation to Improve Visual Function After Optic Neuritis in Persons with Multiple Sclerosis

Optic NeuritisMultiple Sclerosis, Relapsing-Remitting
Technical University of Munich50 enrolled1 locationNCT06389968