RecruitingNCT07627763

Prospective Dynamic Cohort Study of Phenotypic Profiles in Patients With Chronic Obstructive Pulmonary Disease

Prospective Multicenter Dynamic Cohort Study to Evaluate Phenotypic Profiles of Subjects With Chronic Obstructive Pulmonary Disease (COPD-BPCO 2 Study)


Sponsor

Initiatives Bronchopneumopathie Chronique Obstructive (BPCO)

Enrollment

500 participants

Start Date

May 1, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This prospective, multicenter, real-world observational cohort study will describe phenotypic profiles, patient characteristics, and treatments in adults with stable chronic obstructive pulmonary disease (COPD). The profiles observed in the current cohort will be compared with those of patients recruited between 2005 and 2018 in the previous COPD-BPCO 1 cohort. Patients will be followed for at least 3 years as part of routine care, with no study-specific visit or treatment.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Age 18 years or older.
  • Stable COPD, defined as no exacerbation requiring treatment during the previous 4 weeks.
  • Confirmed COPD diagnosis based on post-bronchodilator FEV1/FVC < 70%

Exclusion Criteria3

  • Main diagnosis of bronchiectasis, asthma, or any other significant respiratory disease.
  • Patients under legal protection.
  • Pregnant women.

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Interventions

OTHERRoutine care / no study-specific intervention

Patients will be managed according to usual care at the investigator's discretion. The study does not assign any treatment, medicinal product, or medical device.


Locations(7)

Chu Bordeaux

Bordeaux, France

Chu Lille

Lille, France

Chu Lille

Lille, France

Chu Nancy-Brabois

Nancy, France

Hopital Cochin

Paris, France

Chu Reims

Reims, France

Chu Saint Etienne

Saint-Etienne, France

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NCT07627763


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