RecruitingNot ApplicableNCT07635329

Home-based Vision Rehabilitation Guided by Brain Imaging

Behavioral Rehabilitation Through Image-Guided Home-based Training


Sponsor

Georgetown University

Enrollment

100 participants

Start Date

Jul 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The BRIGHT (Behavioral Rehabilitation Through Image-Guided Home-based Training) study aims to evaluate the effectiveness of image-guided, home-based perceptual training at improving visual performance in individuals with visual field loss. Using a prospective, crossover design, BRIGHT combines visual behavioral testing, neuroimaging, and a home-based intervention. It aims to 1) identify neural pathways that support training-induced visual plasticity; and 2) compare the efficacy of different types of visual training delivered in a home-based setting.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • At least 18 years of age.
  • Capable of providing informed consent and complying with study procedures.
  • Unilateral or bilateral focal brain damage causing visual field loss.
  • At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.
  • Eligible for MRI based on standard safety screening.

Exclusion Criteria3

  • Severe neurological or psychiatric conditions unrelated to the focal lesion that may interfere with study participation or data interpretation.
  • Current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.
  • Ocular disease or disorder.

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Interventions

BEHAVIORALHigh-level perceptual learning-based training

Behavioral intervention consisting of repeated computerized visual discrimination tasks targeting higher-order visual processing

BEHAVIORALLow-level perceptual learning-based training

behavioral intervention consisting of repeated computerized visual discrimination tasks targeting low-level visual processing


Locations(1)

Georgetown University Medical Center

Washington D.C., District of Columbia, United States

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NCT07635329


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