RecruitingNot ApplicableNCT07646262

Gluten-Free vs Mediterranean Diet in Rheumatoid Arthritis

Investigation of the Effects of a Gluten-Free Diet and the Mediterranean Diet on the Inflammatory Index, Disease Activity, and Quality of Life in Patients With Rheumatoid Arthritis.

Sponsor

Hasan Kalyoncu University

Enrollment

66 participants

Start Date

Oct 29, 2025

Study Type

INTERVENTIONAL

Conditions

Rheumatoid Arthritis (RA)

Summary

This study aims to evaluate the effects of different dietary interventions, including gluten-free, Mediterranean, and control diets, on disease activity, quality of life, and dietary inflammatory index in patients with rheumatoid arthritis. Participants will be followed for 12 weeks, and changes in clinical and nutritional outcomes will be assessed.

Eligibility

Min Age: 19 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Control Diet, a behavioral approach called Gluten-Free Diet Group, and others for people with rheumatoid arthritis (ra). The study is currently recruiting participants at 1 location. People eligible for this study include aged 19 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALGluten-Free Diet Group

Participants will follow a gluten-free diet in which all wheat, barley, rye, and their derivatives are eliminated for 12 weeks. The diet focuses on naturally gluten-free foods such as fruits, vegetables, legumes, meat, fish, rice, and corn.

BEHAVIORALMediterranean Diet

Participants will follow a Mediterranean dietary pattern characterized by high intake of fruits, vegetables, whole grains, legumes, olive oil, and fish, with moderate consumption of dairy and low intake of red meat and processed foods for 12 weeks.

BEHAVIORALControl Diet

Participants will continue their habitual diet without any specific dietary restrictions or structured dietary guidance during the 12-week study period.