RecruitingPhase 3NCT07647510

A Phase 3 Study to Evaluate Claseprubart in Adults With Generalized Myasthenia Gravis (EMERGE)

A Phase 3 Global, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Demonstrate the Efficacy, Safety, and Tolerability of Claseprubart (DNTH103) in Patients With Generalized Myasthenia Gravis (EMERGE)


Sponsor

Dianthus Therapeutics

Enrollment

195 participants

Start Date

Jul 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this Phase 3 study is to demonstrate the efficacy, safety, and tolerability of claseprubart in participants with generalized myasthenia gravis (gMG).


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Claseprubart, Claseprubart, and others for people with myasthenia gravis, generalized. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGClaseprubart

IV loading dose on Day 1

DRUGPlacebo

IV infusion on Day 1

COMBINATION_PRODUCTClaseprubart

Prefilled syringe containing claseprubart for SC administration

COMBINATION_PRODUCTPlacebo

Prefilled syringe containing placebo for SC administration


Locations(1)

Cinical Study Site

Fayetteville, North Carolina, United States

View Full Details on ClinicalTrials.gov

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NCT07647510


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