RecruitingPhase 1NCT07654972

A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy

A Phase 1, Randomized, Placebo-Controlled, Single- and Multiple-Ascending Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy


Sponsor

Eli Lilly and Company

Enrollment

108 participants

Start Date

Jun 24, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The main purpose of this study is to understand how safe and well-tolerated LY4174794 is in participants with obesity or overweight who are otherwise healthy. Blood tests will be performed to check how much LY4174794 gets into the bloodstream and how long it takes the body to eliminate it. Participation in this study will last about 35 to 45 weeks (7 to 11 months).


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called LY4174794, a drug called LY4174794, and others for people with obesity and overweight. The study is currently recruiting participants at 3 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGLY4174794

Administered SC.

DRUGLY4174794

Administered IV.

DRUGPlacebo

Administered SC.


Locations(3)

ICON Early Phase Services, LLC

San Antonio, Texas, United States

ICON Early Phase Services, LLC

Salt Lake City, Utah, United States

Lilly Centre for Clinical Pharmacology

Singapore, Singapore

View Full Details on ClinicalTrials.gov

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NCT07654972


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