Effect of Systemic Vitamin D on Dental Implant Osseointegration
Effect of Systemic Vitamin D on Dental Implant Osseointegration in Patients With Vitamin D Deficiency: A Randomized Controlled Clinical Study)
Future University in Egypt
10 participants
Nov 1, 2025
INTERVENTIONAL
Conditions
Summary
The primary goal for any oral implantologist is to obtain satisfactory healing and long-term treatment success. Osseointegration is the key to dental implant success8 and is required to achieve direct structural and functional connection between living bone and the surface of a load-bearing artificial implant, is critical for the long-term success of dental implants. Successful dental implant therapy relies on achieving proper osseointegration, which ensures a stable structural and functional bond between the implant surface and surrounding bone. Although dental implants show a high overall success rate of around 95%.
Eligibility
Inclusion Criteria4
- Adults aged 20-60 with diagnosed vitamin D deficiency (<20 ng/mL).
- Edentulous area in the posterior mandible or maxilla.
- No history of previous dental implant failure, metabolic bone diseases, or conditions affecting bone healing.
- Both genders are included
Exclusion Criteria4
- Severe systemic diseases that could interfere with healing.
- Patients already on vitamin D or calcium supplements.
- Smokers or patients with poor oral hygiene practices.
- Pregnant females
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Interventions
to address the relation between Vitamin D deficiency and Dental implant osseointegration for the identification of the participants whom may be non-responders to the vitamin D treatment
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07684404