RecruitingNot ApplicableNCT07715955

Effect of Probiotics on Appetite Regulation in Adults With Overweight/Obesity

Probiotic Regulation of Food Intake Through Satiety Stimulation and Gut Microbiota Modulation


Sponsor

Maastricht University Medical Center

Enrollment

98 participants

Start Date

Mar 18, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this 16-week randomised, placebo-controlled parallel study is to investigate the effect of a newly formed probiotic supplement on satiety and gut microbiota composition in healthy men and women with overweight or obesity form 20-70 years old. The main question it aims to answer is: Does the probiotic supplement increase feelings of satiety and alter gut microbiota composition? Participants will: * Receive a daily dose of 6 g probiotic supplement (packed in sachets of 3 g) or placebo for 16 weeks. * Visit the research unit 3 times at baseline, week 8 and week 16 of the intervention for blood draws and delivering fecal samples. * Keep a study diary to report deviations from their daily habits and fill in food questionnaires.


Eligibility

Min Age: 20 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Placebo and Probiotic supplementation for people with adults, female, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTProbiotic supplementation

16-week consumption of 6 g/day of probiotic supplement

OTHERPlacebo

16-week consumption of 6 g/day of placebo


Locations(1)

Maastricht University, Department of Nutrition and Movement Sciences

Maastricht, Limburg, Netherlands

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NCT07715955


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