RecruitingPhase 1NCT07738614

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight

A Phase 1, Investigator- and Participant-Blinded, Placebo-Controlled, Randomized, Multiple-Dose Study to Evaluate the Gastric Emptying Delay, Pharmacokinetics, Safety, and Tolerability of Eloralintide in Participants With Obesity or Overweight


Sponsor

Eli Lilly and Company

Enrollment

56 participants

Start Date

Jul 31, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The main purpose of this study is to find out how significantly Eloralintide slows stomach emptying in participants who are overweight or obese. For each participant, the study will last approximately 21 weeks and will include 2 overnight stays in the clinical research unit (CRU) lasting between 4 and 8 days. There will be 13 other visits.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Acetaminophen, a drug called Eloralintide, and others for people with obesity and overweight. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGEloralintide

Administered SC

DRUGPlacebo

Administered SC

DRUGAcetaminophen

Administered Oral Solution


Locations(2)

ICON Early Phase Services

San Antonio, Texas, United States

Lilly Centre for Clinical Pharmacology

Singapore, Singapore

View Full Details on ClinicalTrials.gov

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NCT07738614


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