RecruitingNot ApplicableNCT07792603

Daily Upgrade Trial

TONE UP: Daily Upgrade Trial: Tone, Oxygenation, Neuromood, Energy - Upgrade Evaluation


Sponsor

University of North Carolina, Chapel Hill

Enrollment

44 participants

Start Date

Aug 31, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study evaluates the acute and chronic effects of an essential amino acid supplement (Daily Upgrade EAA+) on metabolomics, amino acid kinetics, metabolic rate, body composition in active adult women. The study consists of an acute randomized double-blind crossover phase comparing EAA+, whey protein isolate, and placebo before high-intensity interval training (HIIT), and a chronic randomized double-blind parallel-arm phase evaluating 3 weeks of EAA+ or placebo supplementation combined with twice-weekly HIIT.


Eligibility

Sex: FEMALEMin Age: 25 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Essential Amino Acid+, a behavioral approach called High intensity Interval Training, and others for people with healthy women. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 25 Years to 45 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIETARY_SUPPLEMENTEssential Amino Acid+

Daily supplementation of essential amino acids

DIETARY_SUPPLEMENTNon-Calorie Placebo

Daily supplementation with non-caloric placebo

BEHAVIORALHigh intensity Interval Training

Twice weekly high intensity interval training for 3 weeks

OTHERNo Exercise

No exercise


Locations(1)

Applied Physiology Laboratory

Chapel Hill, North Carolina, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07792603


Related Trials