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RecruitingNCT07798700

Biofluid Research on Age-Related or Inherited Neurodegeneration

Biofluid Research on Age-Related or Inherited Neurodegeneration (BRAIN)

Sponsor

University of Pennsylvania

Enrollment

1,000 participants

Start Date

Dec 12, 2025

Study Type

OBSERVATIONAL

Conditions

Progressive Supranuclear Palsy (PSP)Primary Progressive Aphasia(PPA)Frontotemporal Degeneration(FTD)Familial Frontotemporal Lobar Degeneration (fFTLD)Alzheimer's Disease(AD)ALS (Amyotrophic Lateral Sclerosis)Parkinson's Disease (PD)Dementia With Lewy Bodies (DLB)Cortical Basal Syndrome (CBS)Posterior Cortical Atrophy(PCA)Primary Lateral Sclerosis (PLS)Fronto-temporal Lobar DementiaParkinson's Disease Dementia (PDD)Limbic-predominant Age-related TDP-43 Encephalopathy (LATE)Primary Muscular Atrophy (PMA)

Summary

The aim of this study is to contribute to and continue to sustain a repository of blood samples, nucleic acid (DNA and/or RNA) samples, family history information, and other demographic information from individuals with age-related neurodegenerative conditions, or their family members who may or may not be at risk for similar conditions. This study will continue to further expand research into the molecular and genetic basis of these diseases and their risk factors.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with als (amyotrophic lateral sclerosis), alzheimer's disease(ad), and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

University of Pennsylvania

Philadelphia, Pennsylvania, United States

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NCT07798700

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