ALS (Amyotrophic Lateral Sclerosis) Clinical Trials

16 recruiting

ALS (Amyotrophic Lateral Sclerosis) Trials at a Glance

16 actively recruiting trials for als (amyotrophic lateral sclerosis) are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Calgary, Chicago, and Copenhagen. Lead sponsors running als (amyotrophic lateral sclerosis) studies include Chulalongkorn University, Centre hospitalier de l'Université de Montréal (CHUM), and Celosia Therapeutics Pty Ltd.

Browse als (amyotrophic lateral sclerosis) trials by phase

Treatments under study

About ALS (Amyotrophic Lateral Sclerosis) Clinical Trials

Looking for clinical trials for ALS (Amyotrophic Lateral Sclerosis)? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new ALS (Amyotrophic Lateral Sclerosis) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about ALS (Amyotrophic Lateral Sclerosis) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting
Not Applicable

Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients

ALS (Amyotrophic Lateral Sclerosis)ALSFTDFrontal Temporal Dementia (FTD)
Centre hospitalier de l'Université de Montréal (CHUM)150 enrolled1 locationNCT06051123
Recruiting

Invasive Home Ventilation in Denmark

Spinal Cord Injuries (SCI)Neuromuscular Diseases (NMD)MSA - Multiple System Atrophy+5 more
Rigshospitalet, Denmark450 enrolled1 locationNCT07467187
Recruiting
Not Applicable

The Swedish BioFINDER 2 Study

DementiaMultiple System AtrophyAlzheimer Disease+10 more
Skane University Hospital2,950 enrolled2 locationsNCT03174938
Recruiting

Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical Approaches

FTDALS (Amyotrophic Lateral Sclerosis)Frontotemporal Dementia (FTD)+3 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta230 enrolled4 locationsNCT06856850
Recruiting
Phase 1

A Study of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis

ALS (Amyotrophic Lateral Sclerosis)
Eli Lilly and Company32 enrolled12 locationsNCT07100119
Recruiting
Phase 2

Tofersen in Non-SOD1 ALS

ALS (Amyotrophic Lateral Sclerosis)
Washington University School of Medicine30 enrolled1 locationNCT07294144
Recruiting
Phase 1

Safety and Tolerability Study of CTx1000 In Participants With Amyotrophic Lateral Sclerosis

ALS (Amyotrophic Lateral Sclerosis)
Celosia Therapeutics Pty Ltd15 enrolled1 locationNCT07401121
Recruiting
Not Applicable

Clinical Outcome Assessment for AT & BCI

Spinal Cord InjuryALS (Amyotrophic Lateral Sclerosis)
Shirley Ryan AbilityLab60 enrolled1 locationNCT07407725
Recruiting
Not Applicable

The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder

Upper ExtremityMuscular Dystrophy, DuchenneNeuromuscular Diseases (NMD)+6 more
Seoul National University Hospital30 enrolled1 locationNCT06363357
Recruiting

Omics Sciences for the Identification of Pathogenetic Mechanisms and Biomarkers in Neurodegenerative Diseases

Alzheimer DiseaseParkinson DiseaseFTD+3 more
Ospedale Policlinico San Martino1,200 enrolled1 locationNCT07235111
Recruiting
Not Applicable

Non-invasive Brain Stimulation and Exercise Intervention for Patients With Motor Neuron Disease

ALS (Amyotrophic Lateral Sclerosis)
Chulalongkorn University100 enrolled1 locationNCT07067229
Recruiting

Amyotrophic Lateral Sclerosis Registry in Thailand

ALS (Amyotrophic Lateral Sclerosis)
Chulalongkorn University100 enrolled1 locationNCT07175935
Recruiting
Not Applicable

At-home Treatment With Cortico-spinal tDCS for Amyotrophic Lateral Sclerosis

ALSALS (Amyotrophic Lateral Sclerosis)
University of Trieste40 enrolled1 locationNCT07006571
Recruiting

ALS Research Collaborative

Amyotrophic Lateral SclerosisMotor Neuron DiseaseALS (Amyotrophic Lateral Sclerosis)+1 more
ALS Therapy Development Institute2,000 enrolled1 locationNCT06885918
Recruiting
Not Applicable

Augmented Reality BCI Longitudinal Study for Persons With Late Stage ALS

ALS (Amyotrophic Lateral Sclerosis)
Cognixion10 enrolled1 locationNCT06810219
Recruiting

Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis

Spinal Muscular AtrophyALS (Amyotrophic Lateral Sclerosis)Postpoliomyelitis Syndrome
University of Dublin, Trinity College400 enrolled1 locationNCT05663008