Magnetic Resonance Imaging of Cerebral Connectivity and Volume in Neurodegeneration and Glaucoma
University Hospital, Bordeaux
100 participants
Aug 28, 2026
INTERVENTIONAL
Conditions
Summary
The EVOLUTION is a 10-year extension of the ENVOL study. It seeks to compare the evolution of structural and functional connectivity (Hub Disruption Index) and cerebral volume on 3T MRI of the brain in glaucoma patients and matched controls. The study aims to examine the hypothesis that glaucomatous optic neuropathy is not limited solely to the visual pathway, but rather is associated with a broader degeneration of the central nervous system.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
MRI
Locations(1)
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NCT07802769