Actinic Keratoses Clinical Trials

9 recruitingLast updated: May 11, 2026

There are 9 actively recruiting actinic keratoses clinical trials across 5 countries. Studies span Not Applicable, Phase 1, Phase 3, Phase 4. Top locations include Dayton, Ohio, United States, Eindhoven, North Brabant, Netherlands, Fairborn, Ohio, United States. Updated daily from ClinicalTrials.gov.


Actinic Keratoses Trials at a Glance

9 actively recruiting trials for actinic keratoses are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Dayton, Eindhoven, and Fairborn. Lead sponsors running actinic keratoses studies include Wright State University, M.D. Anderson Cancer Center, and Cosmetique Active International.

Browse actinic keratoses trials by phase

Treatments under study

About Actinic Keratoses Clinical Trials

Looking for clinical trials for Actinic Keratoses? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Actinic Keratoses trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Actinic Keratoses clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Phase 1

Actinic Keratoses Treated With 5-fluorouracil Plus Aluminum

Actinic Keratoses
West Virginia University32 enrolled1 locationNCT07401277
Recruiting
Phase 3

A Pilot Clinical Trial Comparing Topical Fluorouracil to Fluorouracil Plus Calcipotriene Field Treatments in Patients With Multiple Actinic Keratoses

Multiple Actinic Keratoses
M.D. Anderson Cancer Center30 enrolled1 locationNCT06851507
Recruiting
Not Applicable

Investigation of the Effect of Lipikar Baume AP+M

Actinic Keratoses
CentroDerm GmbH20 enrolled1 locationNCT06385340
Recruiting

SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography

Oral CancerOral Squamous Cell CarcinomaActinic Keratoses+9 more
University of Palermo200 enrolled1 locationNCT06321003
Recruiting
Phase 4

Combination Therapy of 5-Fluorouracil and CALcipotriol Versus 5-Fluorouracil in the Treatment of Actinic Keratosis

Actinic Keratoses
Maastricht University Medical Center232 enrolled4 locationsNCT06499415
Recruiting
Not Applicable

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

Non-melanoma Skin CancerAgingActinic Keratoses
Wright State University72 enrolled1 locationNCT03906253
Recruiting
Not Applicable

The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population

Non-melanoma Skin CancerAgingActinic Keratoses
Wright State University80 enrolled1 locationNCT06428721
Recruiting
Not Applicable

Effect of Lipikar Urea 30% Before Actinic Keratoses Treatment

Actinic Keratoses
Cosmetique Active International100 enrolled1 locationNCT06274320
Recruiting

Randomised, double-blind, placebo controlled study to assess efficacy of oral nicotinamide in the treatment and prevention of actinic keratoses

Actinic Keratoses
Royal Prince Alfred (provide infrastructural support)50 enrolled1 locationACTRN12609000490279