Phase 3 Action Clinical Trials
28 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 28 trials
Recruiting
Phase 3
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
ObesityHeart Failure With Preserved Ejection FractionHeart Failure With Mildly Reduced Ejection Fraction
Amgen5,056 enrolled605 locationsNCT07037459
Recruiting
Phase 2Phase 3
Virtual Menstrual Pain Approaches in Females
Digital HealthAcupressureMetabolomics+5 more
Nanyang Technological University145 enrolled1 locationNCT07497711
Recruiting
Phase 3
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Heart FailureHeart Failure With Reduced Ejection Fraction
Cytokinetics1,800 enrolled185 locationsNCT06736574
Recruiting
Phase 3
Selenium Intervention Registry Randomized Trial in Heart Failure
Cognitive functioningHeart FailureHeart Failure and Reduced Ejection Fraction+4 more
Skane University Hospital4,326 enrolled11 locationsNCT07543562
Recruiting
Phase 3
A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in the United States
Molecular Mechanisms of Pharmacological ActionPeripheral Nervous System AgentsNeurotransmitter Agents+7 more
Merz North America, Inc.300 enrolled28 locationsNCT07122193
Recruiting
Phase 3
A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in Europe (PLATINUM EU)
Molecular Mechanisms of Pharmacological ActionPeripheral Nervous System AgentsNeurotransmitter Agents+7 more
Merz Aesthetics GmbH300 enrolled26 locationsNCT07210463
Recruiting
Phase 2Phase 3
Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy
Heart Failure With Reduced Ejection FractionHeart Rhythm Disorder
Herlev and Gentofte Hospital348 enrolled1 locationNCT06128980
Recruiting
Phase 3
Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)
AnesthesiaAnesthesia ComplicationAnesthesia; Reaction+3 more
University of Texas Southwestern Medical Center200 enrolled1 locationNCT05358535
Recruiting
Phase 3
PRO-232 in Patients Subjected to Cataract Surgery
Cataract Extraction
Laboratorios Sophia S.A de C.V.134 enrolled2 locationsNCT07305987
Recruiting
Phase 2Phase 3
Tailored Exercise Training Study Among Adults With HFpEF
Diabetic CardiomyopathiesHFpEF - Heart Failure With Preserved Ejection Fraction
University of Texas Southwestern Medical Center120 enrolled1 locationNCT07223242
Recruiting
Phase 2Phase 3
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic+2 more
University of Leicester63 enrolled3 locationsNCT05887271
Recruiting
Phase 3
LIMIT Trial - Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema Pallidum Treatment
Syphilis InfectionBenzathine Penicillin Adverse Reaction
Washington University School of Medicine48 enrolled1 locationNCT06391125
Recruiting
Phase 3
Efficacy of Ozone Therapy in Reducing Complications Following Impacted Mandibular Third-molar Surgery
Impacted Mandibular Third Molar Extraction
Jelena Krunic20 enrolled1 locationNCT06802354
Recruiting
Phase 2Phase 3
Dog Presence and Oxytocin on Trust Towards Therapists
Depressive SymptomsHuman-Animal Interaction
Dr. Karin Hediger176 enrolled1 locationNCT06248710
Recruiting
Phase 3
The Effect of Sacubitril/valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients with Ischemic Heart Failure with Mid-range Ejection Fraction
Heart Failure with Moderately Reduced Ejection Fraction
John Paul II Hospital, Krakow666 enrolled1 locationNCT05508035
Recruiting
Phase 3
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
Heart Failure With Preserved Ejection Fraction
Uppsala University2,000 enrolled78 locationsNCT02901184
Recruiting
Phase 3
PREVENTION OF WORSENING RENAL FUNCTION OF INTRAVENUS ALBUMIN IN HEART FAILURE PATIENTS
Heart Failure; With DecompensationDiuretics Drug ReactionsAlbumin; Double
Democritus University of Thrace250 enrolled1 locationNCT06630923
Recruiting
Phase 3
A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure
Heart FailureCardiovascular DiseasesHypertension+5 more
Pulnovo Medical (Wuxi) Co., Ltd.264 enrolled1 locationNCT05824923
Recruiting
Phase 2Phase 3
Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure
ObesityWeight LossHeart Failure With Reduced Ejection Fraction+1 more
Jens D Hove, MD,PHD100 enrolled1 locationNCT06423599
Recruiting
Phase 2Phase 3
GnRH Therapy on Cognition in Down Syndrome
Cognitive DeclineAlzheimer Disease, Early OnsetDown Syndrome+1 more
Nelly Pitteloud56 enrolled1 locationNCT04390646