Phase 3 Acute Ischemic Stroke Clinical Trials

32 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 32 trials

Recruiting
Phase 3

rhTNK-tPA for Acute Ischemic Stroke Under Simplified Imaging in the Extended Time Window

Acute Ischemic Stroke
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University750 enrolled1 locationNCT07606807
Recruiting
Phase 3

Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Acute Ischemic StrokeCerebral Stroke
Pharmazz, Inc.514 enrolled55 locationsNCT05691244
Recruiting
Phase 3

A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well

Acute Ischemic Stroke
Boehringer Ingelheim1,325 enrolled242 locationsNCT07361302
Recruiting
Phase 2Phase 3

Minocycline After Successful Endovascular Thrombectomy Recanalization in Acute Anterior Circulation Large Vessel Occlusion (ATTRACTION-MINOA)

Acute Ischemic StrokeMinocyclineAnterior Circulation Brain Infarction+2 more
Xiang Luo860 enrolled1 locationNCT07594314
Recruiting
Phase 3

Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis

Acute Ischemic StrokeBrain StrokeStenting Treatment
ProMedica Health System342 enrolled1 locationNCT07356284
Recruiting
Phase 2Phase 3

Minocycline After Successful Endovascular Thrombectomy Recanalization in Posterior Circulation Arterial Occlusion (ATTRACTION-MINOP)

Acute Ischemic StrokeMinocyclineArterial Occlusion+2 more
Xiang Luo234 enrolled1 locationNCT07594301
Recruiting
Phase 3

Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE

Atrial FibrillationAcute Ischemic Stroke
Universitätsklinikum Hamburg-Eppendorf1,746 enrolled1 locationNCT05293080
Recruiting
Phase 3

Precision Antiplatelet Therapy Guided by Platelet Aggregation Function in Patients With Acute Ischemic STROKE

Acute Ischemic StrokeClopidogrel Resistance
Sichuan Provincial People's Hospital5,138 enrolled1 locationNCT06853535
Recruiting
Phase 3

Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Anterior Circulation Large Vessel Occlusion Stroke -2

Acute Ischemic Stroke
Capital Medical University692 enrolled53 locationsNCT07263776
Recruiting
Phase 3

OPtimizing REperfusion by Intra-Arterial ThRomboLysis as Adjunct to Endovascular Treatment for Medium Vessel Occlusion

Acute Ischemic Stroke
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University530 enrolled1 locationNCT07137832
Recruiting
Phase 3

Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Therapy -2

Acute Ischemic Stroke
Capital Medical University1,192 enrolled12 locationsNCT07263308
Recruiting
Phase 3

Tenecteplase Before Interhospital Transfer for EVT in Acute Anterior Circulation LVO at 4.5-24 Hours

Acute Ischemic StrokeLarge Vessel OcclusionTransportation of Patients
Xuanwu Hospital, Beijing572 enrolled2 locationsNCT07253181
Recruiting
Phase 2Phase 3

Optimizing Reperfusion to Improve Outcomes and Neurologic Function

Acute Ischemic Stroke
Corxel Pharmaceuticals740 enrolled83 locationsNCT06990867
Recruiting
Phase 2Phase 3

Efficacy and Safety of Early Combined Therapy With PCSK9 Inhibitors and Statins in Acute Ischemic Stroke

Acute Ischemic Stroke
Xiang Luo429 enrolled2 locationsNCT06696820
Recruiting
Phase 3

Outcome in Patients Treated With Endovascular Thrombectomy - optIMAL Blood Pressure Control 2 (OPTIMAL-BP 2)

Acute Ischemic Stroke
Yonsei University176 enrolled1 locationNCT06677970
Recruiting
Phase 2Phase 3

Intra-arterial Recombinant Human Tenecteplase Tissue-type Plasminogen Activator (rhTNK-tPA) Thrombolysis for Acute Medium Vessel Occlusion

Acute Ischemic StrokeMedium Vessel Occlusion
Xiang Luo382 enrolled1 locationNCT07302854
Recruiting
Phase 3

Phase III Clinical Trial of SHPL-49 Injection in the Treatment of Acute Ischemic Stroke

Acute Ischemic Stroke
Shanghai Hutchison Pharmaceuticals Limited1,096 enrolled1 locationNCT07241520
Recruiting
Phase 2Phase 3

UCMSCs as Treatment for Patients With Acute Ischemic Stroke (Stroke Neuroncell-EX)

Acute Ischemic Stroke
Cytopeutics Sdn. Bhd.80 enrolled1 locationNCT06129175
Recruiting
Phase 3

CHinese ischEmic Stroke Beyond 4.5 Hours With TeNecteplase Under Optimized Non-Contrast CT Selection

Acute Ischemic Stroke
Huashan Hospital890 enrolled2 locationsNCT06994975
Recruiting
Phase 3

Early Administration of Tirofiban in Patients Treated With Tenecteplase for Acute Ischemic Stroke

Acute Ischemic Stroke
Second Affiliated Hospital of Guangxi Medical University348 enrolled38 locationsNCT05604638