Phase 4 Acute Clinical Trials

178 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 178 trials

Recruiting
Phase 4

Influence of Human Albumin Supplementation on Kidney Dysfunction After Liver Transplantation

Acute Kidney InjuryLiver Transplantation
Rennes University Hospital400 enrolled8 locationsNCT06535945
Recruiting
Phase 4

Dual Antithrombotic Therapy With Dabigatran and Ticagrelor in Patients With ACS and Non-valvular AF Undergoing PCI

Atrial FibrillationAcute Coronary SyndromeAntithrombotic Therapy+1 more
Medical University of Gdansk1,194 enrolled1 locationNCT04695106
Recruiting
Phase 4

Comparative Effectiveness of Upadacitinib vs Corticosteroids as First-Line Therapy for Acute Severe Ulcerative Colitis(UPFRONT)

Acute Severe Ulcerative Colitis
Yongquan Shi46 enrolled4 locationsNCT07546097
Recruiting
Phase 4

A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine

Acute Treatment of Migraine
Pfizer400 enrolled3 locationsNCT07609914
Recruiting
Phase 4

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

CholangiocarcinomaSolid Tumor MalignanciesGlioma+1 more
Rigel Pharmaceuticals16 enrolled2 locationsNCT07486713
Recruiting
Phase 4

Eduction in ImmunoSuppressive Regimen Among Kidney Transplant Recipients Patients Admitted to the Intensive Care Unit for Septic Shock and/or Acute Respiratory Failure

Acute Respiratory FailureKidney Transplant RecipientsSepsis and septic shock+1 more
University Hospital, Strasbourg, France212 enrolled1 locationNCT06881927
Recruiting
Phase 4

Digoxin After Acute Heart Failure (DIG-DICA)

Acute Heart Failure (AHF)
Hospital General de Agudos "Dr. Cosme Argerich"120 enrolled1 locationNCT07321509
Recruiting
Phase 4

Oral Azacitidine in Transplant-Eligible Patients With Acute Myeloid Leukemia (AML) Suffering From Health-Inequality

Acute Myeloid Leukemia
Virginia Commonwealth University12 enrolled1 locationNCT06370000
Recruiting
Phase 4

Cerebellum-based Imaging Neural Markers for Antipsychotic Response

Psychosis; Acute
Northwell Health120 enrolled1 locationNCT07483294
Recruiting
Phase 4

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

Acute Kidney Injury (AKI)AnesthesiaMyocardial Injury After Noncardiac Surgery (MINS)+4 more
University of California, San Francisco18,000 enrolled10 locationsNCT06802224
Recruiting
Phase 4

Safety and Efficacy of Adjunctive GM1 to Mechanical Thrombectomy for Acute Anterior Circulation Large Vessel Occlusion

StrokeAcute Ischemic Stroke
Xuanwu Hospital, Beijing868 enrolled1 locationNCT07519044
Recruiting
Phase 4

Pre-discharge Influenza Vaccination in Patients Hospitalized for Acute Cardiac Conditions

Myocardial InfarctionAcute Heart Failure (AHF)Arrhythmias+3 more
Wroclaw Medical University400 enrolled1 locationNCT07617376
Recruiting
Phase 4

Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in India

Acute Myeloid Leukemia
AbbVie100 enrolled11 locationsNCT07044687
Recruiting
Phase 4

The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes

Acute Stress ReactionFear of Spiders
Walter Reed Army Institute of Research (WRAIR)88 enrolled1 locationNCT06982183
Recruiting
Phase 4

Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.

Lumbar Spinal StenosisSciatica Acute
Primus Pharmaceuticals50 enrolled24 locationsNCT06157177
Recruiting
Phase 4

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

Acute Lymphoblastic LeukemiaMixed Phenotype Acute LeukemiaLymphoblastic Lymphoma
St. Jude Children's Research Hospital850 enrolled3 locationsNCT06289673
Recruiting
Phase 4

Treatment With Aspirin Alone Versus Aspirin in Combination With Fondaparinux Before Early Coronary Assessment in Patients With Non-ST-Elevation Myocardial Infarction

Acute Myocardial Infarction (AMI)NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)
University of Aarhus5,076 enrolled10 locationsNCT06710184
Recruiting
Phase 4

Short-term Intravenous Fluids for Prevention of Post-ERCP Pancreatitis

Post-ERCP Acute Pancreatitis
University of Calgary505 enrolled1 locationNCT06260878
Recruiting
Phase 4

Study of the Effectiveness and Safety of Daunorubicin /Idarubicin ± Silibinin in Treating Newly Diagnosed AML (Non-M3).

Acute Myeloid LeukemiaChemotherapy EffectNewly Diagnosed
Fujian Medical University Union Hospital100 enrolled1 locationNCT07561892
Recruiting
Phase 4

Low-Dose Tenecteplase for Acute Ischemic Stroke Treatment in Aging Patients

Acute Ischemic Stroke Patients
Southwest Hospital, China798 enrolled49 locationsNCT07294209