Phase 3 Adult Clinical Trials
28 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 28 trials
Recruiting
Phase 3
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
DepressionDepression - Major Depressive DisorderDepression in Adults+3 more
Cybin IRL Limited330 enrolled67 locationsNCT06793397
Recruiting
Phase 3
Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT
Adult Acute Myeloid Leukemia
Priothera SAS366 enrolled108 locationsNCT05429632
Recruiting
Phase 3
Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma
GlioblastomaNeoplastic DiseaseGlioblastoma (GBM)+3 more
Telix Pharmaceuticals (Innovations) Pty Limited50 enrolled4 locationsNCT07100730
Recruiting
Phase 3
Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)
Mild Traumatic Brain InjuryAdult Growth Hormone Deficiency
VA Office of Research and Development172 enrolled4 locationsNCT04867317
Recruiting
Phase 3
A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients
NeoplasmsBrain TumorGlioblastoma+5 more
NaviFUS Corporation32 enrolled2 locationsNCT06496971
Recruiting
Phase 3
A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma
Brain TumorGlioblastomaGBM+1 more
Ivy Brain Tumor Center450 enrolled95 locationsNCT06388733
Recruiting
Phase 2Phase 3
Brentuximab Vedotin for Newly Diagnosed cHL in Chinese CAYA Based on PET/CT Assessment
TreatmentSurvivalClassical Hodgkin Lymphoma+6 more
Children's Cancer Group, China96 enrolled1 locationNCT06563245
Recruiting
Phase 3
Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes
Type 2 Diabetes (Adult Onset)
The University of Texas Health Science Center at San Antonio256 enrolled2 locationsNCT06246799
Recruiting
Phase 3
Comparison of VA and D/IA Induction Regimens in Elderly Fit Acute Myeloid Leukemia Patients
AML, Adult
Institute of Hematology & Blood Diseases Hospital, China240 enrolled1 locationNCT07132684
Recruiting
Phase 2Phase 3
Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo
Post-aggressive ImmunosuppressionAdult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C
Assistance Publique - Hôpitaux de Paris170 enrolled2 locationsNCT06694740
Recruiting
Phase 2Phase 3
HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma
Solid Tumor, AdultAdvanced Intrahepatic Cholangiocarcinoma
Hutchmed235 enrolled1 locationNCT04353375
Recruiting
Phase 3
Evaluation Contact X-ray Brachytherapy for Rectal Preservation in Intermediate Substage Rectal Adenocarcinoma
Adult With Intermediate Low or Mid Rectal Adenocarcinoma
Gustave Roussy, Cancer Campus, Grand Paris212 enrolled11 locationsNCT06402864
Recruiting
Phase 3
Phase III Clinical Study Comparing the Efficacy and Safety of GZR18 Injection and Semaglutide (Wegovy®) in Adult Obese or Overweight Subjects
Obesity/Overweight in Adult
Gan & Lee Pharmaceuticals.420 enrolled1 locationNCT07150975
Recruiting
Phase 2Phase 3
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic+2 more
University of Leicester63 enrolled3 locationsNCT05887271
Recruiting
Phase 3
Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass
Cardiac SurgeryCardiopulmonary BypassNitric Oxide+1 more
Xijing Hospital3,650 enrolled3 locationsNCT06702553
Recruiting
Phase 2Phase 3
Multicenter Study of Combined Chemotherapy and Transplantation for Adult ALL
Acute Lymphoblastic Leukemia, Adult
Shanxi Bethune Hospital50 enrolled1 locationNCT07059156
Recruiting
Phase 3
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
Acute Myeloid Leukemia, Adult
Stichting Hemato-Oncologie voor Volwassenen Nederland415 enrolled67 locationsNCT06652438
Recruiting
Phase 2Phase 3
Treatment Strategy for Relapsed/Refractory Hodgkin Lymphoma
Hodgkin LymphomaRefractory Hodgkin LymphomaRelapsed Hodgkin's Disease, Adult
Hospital Regional de Alta Especialidad del Bajio20 enrolled1 locationNCT05595447
Recruiting
Phase 3
The Preventing Functional Decline in Acutely Hospitalized Older Patients (PREV_FUNC) Study
Older AdultsHospitalization
Karolinska Institutet320 enrolled1 locationNCT05366075
Recruiting
Phase 3
Phase 3 Clinical Trial with Dapagliflozin in Chronic Kidney Disease in Adolescents and Young Adult Patients
Chronic Kidney Failure in Children and Young Adults
University Hospital Goettingen102 enrolled16 locationsNCT05944016