Phase 4 Adult Clinical Trials

37 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 37 trials

Recruiting
Phase 4

Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)

Obstructive Sleep Apnea of Adult
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran50 enrolled1 locationNCT06380491
Recruiting
Phase 4

Longitudinal Tracking of Bone Marrow Plasma Cell Responses to Licensed Human Vaccines

Healthy AdultsImmunology
Washington University School of Medicine25 enrolled1 locationNCT07493460
Recruiting
Phase 4

Post-Operative Thoracolumosacral Orthosis for PJK

Proximal Junctional KyphosisAdult Spinal Deformity SurgeryThoracolumbosacral Orthosis
Hospital for Special Surgery, New York84 enrolled6 locationsNCT06491030
Recruiting
Phase 4

Impact GLP-1 Agonists Following Bariatric

Diabetes MellitusMetabolic SyndromeHypertension+2 more
University of Missouri-Columbia150 enrolled1 locationNCT06132477
Recruiting
Phase 4

Investigation of Locus Coeruleus Function in Sustained Attention

Attention - no Condition is Being Assessed - Healthy Adults
University of California, Davis40 enrolled1 locationNCT06041048
Recruiting
Phase 4

Comparing Dynamic Navigation to Static Navigation in the Implant Placement

Healthy AdultsDental ImplantAccuracy
Ain Shams University20 enrolled1 locationNCT07291336
Recruiting
Phase 4

Sinus Tarsi Implant as an Adjuvant Procedure to Medial Displacement Calcaneal Osteotomy in the Treatment of Mobile Adult Acquired Flatfoot Deformity

Acquired Adult Flatfoot DeformityFlat Foot
Region Skane130 enrolled10 locationsNCT06211504
Recruiting
Phase 4

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

Traumatic Brain InjuryBrain Tumor AdultWound Closure+3 more
University of Michigan160 enrolled1 locationNCT07225101
Recruiting
Phase 4

Efficacy Of Sodium Glucose Transporter Inhibitor (SGLT2I) In Adult Patients With Congenital Heart Disease

Heart FailureAdult Congenital Heart Disease
Anita Saraf40 enrolled3 locationsNCT06260059
Recruiting
Phase 4

Characterizing the Human Airway Immune Response to FluMist Vaccination

Healthy Young AdultsInfluenza VaccinesInfluenza Vaccine Response
Washington University School of Medicine30 enrolled1 locationNCT07177417
Recruiting
Phase 4

Oral vs IV Sedation for Cataract Surgery in Older Adults

Older AdultsSedationPerioperative Care+2 more
University of California, San Francisco20 enrolled1 locationNCT07154147
Recruiting
Phase 4

The Analgesic Effect of Scalp Nerve Block Using Bupivacaine Liposomes for Postoperative Pain Relief After Craniotomy

Cerebrovascular DiseaseBrain Tumor Adult
Zhejiang University218 enrolled1 locationNCT07049094
Recruiting
Phase 4

The Effects of Ferric Derisomaltose on Postoperative Anemia in Spinal Deformity Surgery

SurgeryAdultSpinal Deformity+1 more
Peking Union Medical College Hospital120 enrolled1 locationNCT05714007
Recruiting
Phase 4

Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac Surgery

EsketamineDexmedetomidineAdults+2 more
Peking University First Hospital476 enrolled1 locationNCT06859892
Recruiting
Phase 4

Long Acting Cabotegravir Plus Rilpivirine in People Living with HIV-1 Aged ≥ 60 Years for 24 Months.

HIV-1 Infected Adults with Controlled Viremia
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia120 enrolled8 locationsNCT06646562
Recruiting
Phase 4

Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis

Bronchiectasis Adult
Shanghai Pulmonary Hospital, Shanghai, China364 enrolled63 locationsNCT06093191
Recruiting
Phase 4

Pharmacokinetic-guided Dosing of Emicizumab

AdultHemophilia A With InhibitorAdolescent+3 more
Kathelijn Fischer95 enrolled8 locationsNCT06320626
Completed
Phase 4

Pilot study of a branded (marketed) formulation betamethasone dipropionate called Diprosone® OV ointment applied to the skin in healthy male and female volunteers to determine the appropriate dose duration (ED50) for use in a pivotal in vivo bioequivalence study.

Diprosone OV ointment is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited12 enrolled1 locationACTRN12623001181695
Completed
Phase 4

Pilot study of a branded (marketed) formulation betamethasone dipropionate called Diprosone® ointment applied to the skin in healthy male and female volunteers to determine the appropriate dose duration (ED50) for use in a pivotal in vivo bioequivalence study.

Diprosone ointment is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited12 enrolled1 locationACTRN12623001179628
Completed
Phase 4

Pilot study of a branded (marketed) formulation betamethasone dipropionate called Diprosone® cream applied to the skin in healthy male and female volunteers to determine the appropriate dose duration (ED50) for use in a pivotal in vivo bioequivalence study.

Diprosone cream is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited12 enrolled1 locationACTRN12623000887673