Early Phase 1 Adult Clinical Trials

12 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 112 of 12 trials

Recruiting
Early Phase 1

The Dosimetry, Safety and Diagnostic Efficacy of ⁶⁸Ga-FC516 in Healthy Subjects and Patients With Prostate Cancer

Prostate CancerHealthy Adult
FindCure Biosciences (ZhongShan) Co., Ltd.10 enrolled1 locationNCT07468708
Recruiting
Early Phase 1

Hyperpolarized Carbon-13 Alpha-ketoglutarate Imaging in IDH Mutant Glioma

Adult Gliomas, Mixed
Robert Bok, MD, PhD40 enrolled1 locationNCT05851378
Recruiting
Early Phase 1

Safety and Efficacy of Klotho and Follistatin Gene Therapy

Healthy Adults
Minicircle30 enrolled2 locationsNCT07285629
Recruiting
Early Phase 1

Clinical Study of LV009 Injection for the Treatment of Relapsed/Refractory CD19-Positive Hematologic and Lymphoid Malignancies

Acute Lymphoblastic Leukemia (ALL), AdultNon-Hodgkin Lymphoma (NHL)
PersonGen BioTherapeutics (Suzhou) Co., Ltd.19 enrolled1 locationNCT07312630
Recruiting
Early Phase 1

NIR-II Fluorescence-Guided Hepatectomy Using ICG-Cisplatin Nanoprobes for HCC

Liver Cancer, Adult
West China Hospital30 enrolled1 locationNCT07295262
Recruiting
Early Phase 1

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Multiple MyelomaLymphomaHematologic Malignancy+5 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins8 enrolled1 locationNCT06398457
Recruiting
Early Phase 1

The Effect of Oral Oxytocin and Atosiban on Top-down Attention ( OTAtosiban )

Healthy Adult Male
University of Electronic Science and Technology of China250 enrolled1 locationNCT07140237
Recruiting
Early Phase 1

A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors

Head and Neck Squamous Cell CarcinomaSoft Tissue Sarcoma Adult
Pure Biologics S.A.12 enrolled1 locationNCT06700070
Recruiting
Early Phase 1

GT101 Injection in the Treatment of Metastatic/Recurrent Advanced Solid Tumors

Adult
Grit Biotechnology20 enrolled1 locationNCT06077903
Recruiting
Early Phase 1

Autologous Tumor Infiltrating Lymphocyte Injection for the Treatment of Advanced Solid Tumors

Solid TumorAdultGT316
Grit Biotechnology36 enrolled1 locationNCT06094426
Recruiting
Early Phase 1

Clinical Study of GT201 in the Treatment of Advanced Gynecological Tumors

Adult Gynecological Tumors
Grit Biotechnology26 enrolled1 locationNCT06834542
Recruiting
Early Phase 1

Allogeneic CD19-targeted CAR-γδT Cell Infusion Therapy in Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia

B-Cell Acute Lymphoblastic Leukemia, Adult
The First Affiliated Hospital of Soochow University18 enrolled1 locationNCT06696833