Phase 1 Advanced Melanoma Clinical Trials
11 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–11 of 11 trials
Recruiting
Phase 1
IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Stage IIIA Uterine Corpus Cancer AJCC v8+35 more
M.D. Anderson Cancer Center54 enrolled1 locationNCT05039801
Recruiting
Phase 1Phase 2
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+97 more
Mayo Clinic132 enrolled1 locationNCT05269381
Recruiting
Phase 1
AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
Advanced MelanomaAdvanced Melanoma and Normal or Impaired
Yale University50 enrolled1 locationNCT07027488
Recruiting
Phase 1Phase 2
A Clinical Study of T3011 in Subjects With Advanced Melanoma
Advanced Melanoma
Shanghai Pharmaceuticals Holding Co., Ltd42 enrolled7 locationsNCT06214156
Recruiting
Phase 1Phase 2
A Trial of LBL-024 Monotherapy, LBL-024 Combined With LBL-007 or Toripalimab in Patients With Advanced Melanoma
Advanced Melanoma
Nanjing Leads Biolabs Co.,Ltd200 enrolled15 locationsNCT07099430
Recruiting
Phase 1
Naltrexone and Propranolol Combined With Immunotherapy
Advanced Melanoma
Sarah Weiss12 enrolled1 locationNCT05968690
Recruiting
Phase 1
Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors
Metastatic MelanomaAdvanced Melanoma
Washington University School of Medicine33 enrolled1 locationNCT05629546
Recruiting
Phase 1
A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma
Advanced Melanoma
Yana Najjar30 enrolled1 locationNCT03311308
Recruiting
Phase 1
The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors
Anatomic Stage III Breast Cancer AJCC v8Advanced Colorectal CarcinomaAdvanced Malignant Solid Neoplasm+4 more
University of California, Davis100 enrolled1 locationNCT05967533
Recruiting
Phase 1
NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma
SarcomaAdvanced MelanomaMelanoma Metastatic
Centre Hospitalier Universitaire Vaudois9 enrolled2 locationsNCT06889766
Recruiting
Phase 1
Gallium Imaging Pilot Study in Metastatic Melanoma
Locally Advanced MelanomaMetastatic Melanoma
Alpha-9 Theranostics Australia Pty Ltd30 enrolled1 locationACTRN12624000085572