Phase 2 Advanced Melanoma Clinical Trials

12 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 112 of 12 trials

Recruiting
Phase 2

A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma

Advanced Melanoma
Memorial Sloan Kettering Cancer Center88 enrolled12 locationsNCT06594991
Recruiting
Phase 2

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

Advanced Colorectal CarcinomaAdvanced Anal CarcinomaAdvanced Biliary Tract Carcinoma+41 more
Mayo Clinic220 enrolled2 locationsNCT05969860
Recruiting
Phase 2

Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma

MelanomaAdvanced MelanomaMelanoma Stage IV+1 more
H. Lee Moffitt Cancer Center and Research Institute90 enrolled1 locationNCT06295159
Recruiting
Phase 1Phase 2

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+97 more
Mayo Clinic132 enrolled1 locationNCT05269381
Recruiting
Phase 2

A Phase II Trial of LM103 in Advanced Melanoma

Advanced Melanoma
Suzhou BlueHorse Therapeutics Co., Ltd.92 enrolled1 locationNCT07310784
Recruiting
Phase 2

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8+26 more
M.D. Anderson Cancer Center50 enrolled1 locationNCT04771520
Recruiting
Phase 1Phase 2

A Clinical Study of T3011 in Subjects With Advanced Melanoma

Advanced Melanoma
Shanghai Pharmaceuticals Holding Co., Ltd42 enrolled7 locationsNCT06214156
Recruiting
Phase 1Phase 2

A Trial of LBL-024 Monotherapy, LBL-024 Combined With LBL-007 or Toripalimab in Patients With Advanced Melanoma

Advanced Melanoma
Nanjing Leads Biolabs Co.,Ltd200 enrolled15 locationsNCT07099430
Recruiting
Phase 2Phase 3

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

Advanced Melanoma
Eikon Therapeutics740 enrolled77 locationsNCT06697301
Recruiting
Phase 2

Prophylactic Mesalamine to Prevent Colitis Following Treatment With Ipilimumab/Nivolumab (Ipi/Nivo)

Advanced MelanomaDiarrheaImmune-related Adverse Event+1 more
AHS Cancer Control Alberta20 enrolled1 locationNCT05663775
Active
Phase 2

Phase Ib/II study of Azacitidine and Carboplatin priming for Ipilimumab and Nivolumab re-challenge in patients with advanced melanoma who are resistant to immunotherapy.

Advanced Melanoma
University of Newcastle27 enrolled2 locationsACTRN12621001155886
Not Yet Recruiting
Phase 2

An Open Label, Multi Centre, Phase II Study to Evaluate the Safety and Efficacy of Coramsine Injection in Patients with Melanoma

Advanced Melanoma
Solbec Pharmaceuticals Ltd56 enrolled1 locationACTRN12606000330549