Phase 2 Advanced Soft Tissue Sarcoma Clinical Trials

10 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 110 of 10 trials

Recruiting
Phase 2

Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial

Metastatic Alveolar Soft Part SarcomaAdvanced Soft Tissue SarcomaAdvanced Alveolar Soft Part Sarcoma+2 more
National Cancer Institute (NCI)27 enrolled13 locationsNCT05333458
Recruiting
Phase 1Phase 2

Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma

Metastatic Soft Tissue SarcomaMetastatic LeiomyosarcomaAdvanced Soft Tissue Sarcoma+5 more
National Cancer Institute (NCI)74 enrolled1 locationNCT06498648
Recruiting
Phase 2

Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas

Metastatic Soft Tissue SarcomaAdvanced Soft Tissue Sarcoma
University of Colorado, Denver65 enrolled1 locationNCT04028063
Recruiting
Phase 2

Pegylated Liposomal Doxorubicin (PLD) Versus Active Surveillance for Advanced Soft Tissue Sarcoma Patients Who Had Controlled Disease After Standard Anthracycline-based Treatment (MELODY)

Advanced Soft Tissue Sarcoma
National Health Research Institutes, Taiwan81 enrolled7 locationsNCT06981637
Recruiting
Phase 2

Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas

OsteosarcomaEwing SarcomaSoft Tissue Sarcoma Adult+2 more
Institut Bergonié119 enrolled10 locationsNCT05182164
Recruiting
Phase 2

Bintrafusp Alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma

Metastatic Soft Tissue SarcomaAdvanced Soft Tissue Sarcoma
Institut Bergonié80 enrolled8 locationsNCT04874311
Recruiting
Phase 2

A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma

Advanced Soft Tissue Sarcoma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology53 enrolled1 locationNCT06367075
Recruiting
Phase 1Phase 2

Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor

Advanced Solid TumorAdvanced Soft Tissue SarcomaAdvanced L-sarcomas+2 more
Grupo Espanol de Investigacion en Sarcomas195 enrolled4 locationsNCT05146440
Recruiting
Phase 1Phase 2

SAINT:Trabectedin, Ipilimumab and Nivolumab for Previously Treated Advanced Soft Tissue Sarcoma

Metastatic Soft Tissue SarcomaAdvanced Soft Tissue Sarcoma
Sarcoma Oncology Research Center, LLC250 enrolled1 locationNCT03138161
Recruiting
Phase 1Phase 2

LINNOVATE: Lurbinectedin, Ipilimumab and Nivolumab for Soft Tissue Sarcoma

Advanced Soft Tissue Sarcoma
ERLINDA M GORDON40 enrolled1 locationNCT05876715