Early Phase 1 Advanced Solid Tumor Clinical Trials

16 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 116 of 16 trials

Recruiting
Early Phase 1

NK521 in the Treatment of Malignant Ascites Associated With Advanced Solid Tumors

Advanced Solid Tumors
Base Therapeutics (Shanghai) Co., Ltd.18 enrolled1 locationNCT07561437
Recruiting
Early Phase 1

Clinical Study on the Efficacy and Safety of CAR-DC in the Treatment of Advanced Solid Tumors

Advanced Solid Tumors
Peking University Shenzhen Hospital10 enrolled1 locationNCT07504445
Recruiting
Early Phase 1

A Single-Arm, Open-Label Clinical Study GK01 Cell Injection in Subjects With Advanced Solid Tumors.

Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD10 enrolled1 locationNCT07414316
Recruiting
Early Phase 1

HEAT Trial (HER2 Antibody Therapy With Lutetium-177)

Advanced Solid TumorsHER2 Gene Mutation
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06824155
Recruiting
Early Phase 1

A Clinical Study of GK02 in Malignant Ascites

Malignant Ascites Caused by Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD9 enrolled1 locationNCT07378436
Recruiting
Early Phase 1

Safety and Efficacy of Metabolically Armed Tumor-Infiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors

Advanced Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences36 enrolled1 locationNCT07349160
Recruiting
Early Phase 1

A Study of TIL in Advanced Solid Tumors (DFGD)

Advanced Solid TumorTreatment Side EffectsEffects of Immunotherapy+1 more
Shanghai Juncell Therapeutics30 enrolled1 locationNCT06488950
Recruiting
Early Phase 1

A Study of GC101 TIL in Advanced Solid Tumors (TR)

Advanced Solid Tumors
Shanghai Juncell Therapeutics20 enrolled1 locationNCT04967833
Recruiting
Early Phase 1

Safety and Efficacy of Metabolically Armed Tumor-lnfiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors

Advanced Solid Tumors
Anhui Provincial Hospital36 enrolled1 locationNCT07106814
Recruiting
Early Phase 1

HF50 in HER-2 Positive and Low-expression Advanced Solid Tumors

Advanced Solid Tumors
HighField Biopharmaceuticals Corporation10 enrolled1 locationNCT06822998
Recruiting
Early Phase 1

AMT-676 in Patients With Advanced Solid Tumors

Advanced Solid Tumors
Multitude Therapeutics Inc.24 enrolled13 locationsNCT06400485
Recruiting
Early Phase 1

An Exploratory Study of Individualized Neo-antigen mRNA Cancer Vaccine InnoPCV in Advanced Solid Tumor Treatment

Advanced Solid Tumor
The Affiliated Hospital Of Guizhou Medical University40 enrolled1 locationNCT06497010
Recruiting
Early Phase 1

Combination Therapy of Personalized mRNA-0217 Vaccines and Pembrolizumab in Patients With Advanced Solid Tumors

Advanced Solid Tumor
Ruijin Hospital34 enrolled1 locationNCT05916248
Recruiting
Early Phase 1

Safety and Preliminary Efficacy of Anti-CDH17 CAR-T Cell Therapy in Patients with CDH17-positive Advanced Solid Tumors

CDH17-positive Advanced Solid Tumors
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China30 enrolled1 locationNCT06820424
Recruiting
Early Phase 1

A Dose Escalation and Dose Expansion Trial of WTX212A in the Treatment of Patients with Advanced Malignant Tumors

Unresectable or Metastatic Advanced Solid Tumors
Zhejiang University44 enrolled1 locationNCT06026605
Recruiting
Early Phase 1

A Clinical Study on TIL for the Treatment of Advanced Solid Tumors

Advanced Solid TumorTreatment Side EffectsEffects of Immunotherapy+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05087745