Phase 2 Advanced Urothelial Carcinoma Clinical Trials

10 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 110 of 10 trials

Recruiting
Phase 2

Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC)

Urothelial CarcinomaAdvanced Urothelial CarcinomaUrothelial Carcinoma Recurrent
Sun Yat-sen University96 enrolled6 locationsNCT07241793
Recruiting
Phase 1Phase 2

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+97 more
Mayo Clinic132 enrolled1 locationNCT05269381
Recruiting
Phase 2

Pembrolizumab Maintenance After Enfortumab Vedotin (EV)/Pembro Induction in Front-Line Metastatic Urothelial Carcinoma

Metastatic Urothelial CarcinomaUnresectable Urothelial CarcinomaAdvanced Urothelial Carcinoma
Fox Chase Cancer Center97 enrolled1 locationNCT07221942
Recruiting
Phase 2

Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma

Locally Advanced Urothelial CarcinomaOligo-metastaic Urothelial Carcinoma
Yale University32 enrolled1 locationNCT07048457
Recruiting
Phase 2

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Urothelial CarcinomaEsophageal CarcinomaHepatocellular Carcinoma+28 more
Mayo Clinic50 enrolled1 locationNCT06265285
Recruiting
Phase 1Phase 2

Clofarabine Therapy in Locally Advanced or Metastatic Urothelial Carcinoma

Advanced Urothelial CarcinomaMetastatic Urothelial Cancer
Ekaterina Laukhtina50 enrolled1 locationNCT07034053
Recruiting
Phase 2

Probiotics in Advanced Urothelial Carcinoma

ImmunotherapyAdvanced Urothelial CarcinomaProbiotics
Sun Yat-sen University222 enrolled3 locationsNCT06904573
Recruiting
Phase 1Phase 2

A Trial of SHR-A2102 With Antitumor Therapy in Advanced Urothelial Carcinoma

Advanced Urothelial Carcinoma
Shanghai Hengrui Pharmaceutical Co., Ltd.90 enrolled1 locationNCT06639347
Recruiting
Phase 1Phase 2

9MW2821 Combined With Toripalimab Injection in Subjects With Local Advanced or Metastatic Urothelial Cancer

Advanced Urothelial Carcinoma
Mabwell (Shanghai) Bioscience Co., Ltd.100 enrolled1 locationNCT06079112
Recruiting
Phase 2

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Metastatic Gastroesophageal Junction Adenocarcinoma+30 more
Northwestern University94 enrolled1 locationNCT05733000