Phase 4 Affect Clinical Trials
16 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–16 of 16 trials
Recruiting
Phase 4
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled19 locationsNCT07105111
Recruiting
Phase 4
The Stimulation To Induce Mothers Study
Labor PainOxytocinPhysiologic Effects of Drugs+1 more
Yale University988 enrolled3 locationsNCT05079841
Recruiting
Phase 4
Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder
ObesityWeight LossBipolar I Disorder+3 more
Mayo Clinic100 enrolled1 locationNCT07213466
Recruiting
Phase 4
Anticholinergic Deprescription in Schizophrenia
SchizophreniaSchizoaffective Disorder
Deepak K. Sarpal, M.D.105 enrolled1 locationNCT06562608
Recruiting
Phase 4
CLOZAPINE Response in Biotype-1
SchizophreniaSchizoaffective DisorderBipolar 1 Disorder
University of Texas Southwestern Medical Center524 enrolled5 locationsNCT04580134
Recruiting
Phase 4
Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial
SchizophreniaSchizoaffective Disorder
New York State Psychiatric Institute280 enrolled7 locationsNCT05208190
Recruiting
Phase 4
Exercise and Olanzapine-samidorphan
Schizoaffective DisorderSchizophenia DisorderBipolar Disorder I or II+1 more
New York State Psychiatric Institute30 enrolled1 locationNCT06740890
Recruiting
Phase 4
Oxytocin and Fetal Heart Rate Changes
Fetal Heart Rate or Rhythm Abnormality Affecting FetusFetal Bradycardia Complicating Labor and DeliveryFetal Bradycardia During Labor
Unyime Ituk730 enrolled2 locationsNCT03232918
Recruiting
Phase 4
Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia
SchizophreniaSchizo Affective Disorder
University of Massachusetts, Worcester50 enrolled1 locationNCT06174116
Recruiting
Phase 4
Open Label Trial Studying the Safety and Effectiveness of ILUVIEN® (190μg) in Children and Adolescents, Who Have Recurrent Non-infectious Uveitis Affecting the Posterior Segment of the Eye.
Non-infectious Uveitis Affecting the Posterior Segment of the Eye
Alimera Sciences25 enrolled6 locationsNCT06539481
Recruiting
Phase 4
Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia
SchizophreniaSchizoaffective Disorder
Centre for Addiction and Mental Health30 enrolled1 locationNCT02639702
Recruiting
Phase 4
Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA
Preterm LaborPreterm BirthRupture of Membranes; Delayed Delivery (Following Spontaneous Rupture)+3 more
Woman's34 enrolled1 locationNCT04047849
Recruiting
Phase 4
Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates
SchizophreniaTobacco SmokingParkinsonism+2 more
Corporal Michael J. Crescenz VA Medical Center10 enrolled1 locationNCT03495024
Recruiting
Phase 4
A single-arm, open-label, pilot study evaluating the efficacy and safety of directly observed peginterferon alfa-2a with ribavirin in conjunction with a peer counsellor in patients actively using injecting drugs who have chronic hepatitis C and attend a drug and alcohol centre.
Chronic hepatitis C virus (HCV) infection.Side effects related to chronic Hepatitis C virus (HCV) infection and treatment in active injecting drug users (IDUs).Factors affecting compliance of active injecting drug users (IDUs) for standard pharmacotherapy treatment of chronic Hepatitis C virus (HCV) infection.+1 more
Dr Joe Sasadeusz50 enrolled1 locationACTRN12608000400369
Completed
Phase 4
Neuroprotective Properties of Quetiapine versus Lithium in a First Episode Mania Cohort: 12-month Neuroanatomical, Neurochemical and Neuro-cognitive Effects and Preliminary Data of Prophylactic Properties
First episode mania (bipolar and schizoaffective illnesses)
The University of Melbourne66 enrolled1 locationACTRN12607000639426
Recruiting
Phase 4
Switching to aripiprazole from other second-generation antipsychotics.
Schizophrenic and schizoaffective disorder
Bristol Meyers Squibb Pharmaceuticals40 enrolled1 locationACTRN12605000516684